N-methylamino>benzoyl>-L-α-glutamyl>-L-glutamic acid tribenzyl ester

Base Information

Chemical Name:N-methylamino>benzoyl>-L-α-glutamyl>-L-glutamic acid tribenzyl ester
CAS No.:79974-13-3
Molecular Formula:C₄₇H₄₇N₃O₁₀
Molecular Weight:813.904
Hs Code.:

N-<N-<4-<<(benzyloxy)carbonyl>methylamino>benzoyl>-L-α-glutamyl>-L-glutamic acid tribenzyl ester

Synonyms:N-methylamino>benzoyl>-L-α-glutamyl>-L-glutamic acid tribenzyl ester

Suppliers and Price of N-methylamino>benzoyl>-L-α-glutamyl>-L-glutamic acid tribenzyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-methylamino>benzoyl>-L-α-glutamyl>-L-glutamic acid tribenzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-methylamino>benzoyl>-L-α-glutamyl>-L-glutamic acid tribenzyl ester

There total 7 articles about N-methylamino>benzoyl>-L-α-glutamyl>-L-glutamic acid tribenzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4561-10-8
L-glutamic acid dibenzyl ester hydrochloride

: (S)-4-[4-(Benzyloxycarbonyl-methyl-amino)-benzoylamino]-5-isobutoxycarbonyloxy-5-oxo-pentanoic acid benzyl ester

: 79974-13-3
N-methylamino>benzoyl>-L-α-glutamyl>-L-glutamic acid tribenzyl ester

Guidance literature:: With triethylamine; In 1,4-dioxane; N,N-dimethyl-formamide; at 25 ℃; for 2h; Yield given;
DOI:10.1021/jm00344a018

Reference yield:

: 1676-73-9,25014-27-1
L-glutamic acid γ-benzyl ester

: 79974-13-3
N-methylamino>benzoyl>-L-α-glutamyl>-L-glutamic acid tribenzyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 68 percent / (i-Pr)2NEt / dioxane; H₂O

2: Et₃N / dimethylformamide; dioxane / 1 h / -10 °C

3: Et₃N / dimethylformamide; dioxane / 2 h / 25 °C

With triethylamine; N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; water; N,N-dimethyl-formamide;
DOI:10.1021/jm00344a018

Reference yield:

: 10541-83-0,937737-33-2
N-methyl-p-aminobenzoic acid

: 79974-13-3
N-methylamino>benzoyl>-L-α-glutamyl>-L-glutamic acid tribenzyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 86 percent / 2 N NaOH / dioxane; H₂O / 0.5 h / 0 - 5 °C

2: 99 percent / SOCl₂ / benzene / 2 h / Heating

3: 68 percent / (i-Pr)2NEt / dioxane; H₂O

4: Et₃N / dimethylformamide; dioxane / 1 h / -10 °C

5: Et₃N / dimethylformamide; dioxane / 2 h / 25 °C

With sodium hydroxide; thionyl chloride; triethylamine; N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; water; N,N-dimethyl-formamide; benzene;
DOI:10.1021/jm00344a018