P-(1,1-dimethylethyl)-P-phenylphosphinoselenoic acid Se-methyl ester

Base Information

• Chemical Name: P-(1,1-dimethylethyl)-P-phenylphosphinoselenoic acid Se-methyl ester
• CAS No.: 113502-18-4
• Molecular Formula: C₁₁H₁₇OPSe
• Molecular Weight: 275.189
• Mol file: 113502-18-4.mol

Synonyms:P-(1,1-dimethylethyl)-P-phenylphosphinoselenoic acid Se-methyl ester

Chemical Property of P-(1,1-dimethylethyl)-P-phenylphosphinoselenoic acid Se-methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of P-(1,1-dimethylethyl)-P-phenylphosphinoselenoic acid Se-methyl ester

There total 5 articles about P-(1,1-dimethylethyl)-P-phenylphosphinoselenoic acid Se-methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

t-butyl phenyl selenophosphinic acid (51584-27-1,51584-28-2) + methyl iodide (74-88-4) → P-(1,1-dimethylethyl)-P-phenylphosphinoselenoic acid Se-methyl ester (113502-18-4)

Guidance literature:

With triethylamine; In dichloromethane;

Reference yield:

tert-butylchlorophenylphosphane (29949-69-7,146387-73-7,146387-74-8) → P-(1,1-dimethylethyl)-P-phenylphosphinoselenoic acid Se-methyl ester (113502-18-4)

Guidance literature:

Multi-step reaction with 3 steps

1: Se / toluene / 1 h / Heating

2: NaOH / acetonitrile / 24 h / 20 °C

3: 0.270 g / acetonitrile / 1 h / 20 °C

With sodium hydroxide; selenium; In toluene; acetonitrile;

DOI:10.1021/jo0484979

Reference yield:

Dichlorophenylphosphine (644-97-3) → P-(1,1-dimethylethyl)-P-phenylphosphinoselenoic acid Se-methyl ester (113502-18-4)

Guidance literature:

Multi-step reaction with 4 steps

1: tetrahydrofuran / 1 h / 0 °C

2: Se / toluene / 1 h / Heating

3: NaOH / acetonitrile / 24 h / 20 °C

4: 0.270 g / acetonitrile / 1 h / 20 °C

With sodium hydroxide; selenium; In tetrahydrofuran; toluene; acetonitrile;

DOI:10.1021/jo0484979

upstream raw materials:

t-butyl phenyl selenophosphinic acid

methyl iodide

tert-butylchlorophenylphosphane

Dichlorophenylphosphine

Downstream raw materials:

tert-butylphenylphosphinic acid chloride

tert-butyl(phenyl)phosphonic acid bromide

t-butyl phenyl phosphinic trifluoroacetate

tert-butylphenylphosphinic acid methyl ester