methyl 5-(2-(allyloxy)-5-(trifluoromethyl)phenyl)-2-(2,6-difluorobenzamido)thiazole-4-carboxylate

Base Information

Chemical Name:methyl 5-(2-(allyloxy)-5-(trifluoromethyl)phenyl)-2-(2,6-difluorobenzamido)thiazole-4-carboxylate
CAS No.:945227-07-6
Molecular Formula:C₂₂H₁₅F₅N₂O₄S
Molecular Weight:498.43
Hs Code.:

Synonyms:methyl 5-(2-(allyloxy)-5-(trifluoromethyl)phenyl)-2-(2,6-difluorobenzamido)thiazole-4-carboxylate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of methyl 5-(2-(allyloxy)-5-(trifluoromethyl)phenyl)-2-(2,6-difluorobenzamido)thiazole-4-carboxylate

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Technology Process of methyl 5-(2-(allyloxy)-5-(trifluoromethyl)phenyl)-2-(2,6-difluorobenzamido)thiazole-4-carboxylate

There total 1 articles about methyl 5-(2-(allyloxy)-5-(trifluoromethyl)phenyl)-2-(2,6-difluorobenzamido)thiazole-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 945227-09-8
C₁₅H₁₃F₃N₂O₃S

: 18063-02-0
2,6-difluorobenzoylchloride

: 945227-07-6
methyl 5-(2-(allyloxy)-5-(trifluoromethyl)phenyl)-2-(2,6-difluorobenzamido)thiazole-4-carboxylate

Guidance literature:: With triethylamine; dmap; In dichloromethane; at 20 ℃;

Reference yield: 79.0%

: 945227-07-6
methyl 5-(2-(allyloxy)-5-(trifluoromethyl)phenyl)-2-(2,6-difluorobenzamido)thiazole-4-carboxylate

: C₁₈H₇F₅N₂O₃S

Guidance literature:: methyl 5-(2-(allyloxy)-5-(trifluoromethyl)phenyl)-2-(2,6-difluorobenzamido)thiazole-4-carboxylate; With pyrrolidine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; at 65 ℃; for 2h;

With trifluoroacetic acid; In tetrahydrofuran; at 65 ℃; for 2h;