Diphenyl-<2,2,2-trifluor-1-(trifluormethyl)ethyl>phosphinsaeureester

Base Information

• Chemical Name: Diphenyl-<2,2,2-trifluor-1-(trifluormethyl)ethyl>phosphinsaeureester
• CAS No.: 21223-05-2
• Molecular Formula: C₁₅H₁₁F₆O₂P
• Molecular Weight: 368.215
• Mol file: 21223-05-2.mol

Synonyms:Diphenyl-<2,2,2-trifluor-1-(trifluormethyl)ethyl>phosphinsaeureester

Chemical Property of Diphenyl-<2,2,2-trifluor-1-(trifluormethyl)ethyl>phosphinsaeureester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Diphenyl-<2,2,2-trifluor-1-(trifluormethyl)ethyl>phosphinsaeureester

There total 9 articles about Diphenyl-<2,2,2-trifluor-1-(trifluormethyl)ethyl>phosphinsaeureester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2,2-Diphenyl-4,4,5,5-tetrakis(trifluormethyl)-1,3,2λ5-dioxaphospholan → Diphenyl-<2,2,2-trifluor-1-(trifluormethyl)ethyl>phosphinsaeureester (21223-05-2)

Guidance literature:

With dimethyl sulfoxide; for 24h; Ambient temperature;

Reference yield: 78.0%

1,1,1,3',3',3'-hexafluoro-propanol (920-66-1) + Diphenylphosphine oxide (4559-70-0) → Diphenyl-<2,2,2-trifluor-1-(trifluormethyl)ethyl>phosphinsaeureester (21223-05-2)

Guidance literature:

With ethyl bromoacetate; 1,8-diazabicyclo[5.4.0]undec-7-ene; In ethyl acetate; at 40 ℃; for 6h; Schlenk technique; Inert atmosphere;

DOI:10.1021/acs.joc.1c02933

Reference yield: 16.0%

C34H22F18O3P2 → diphenyl-phosphinic acid (1707-03-5) + Diphenyl-<2,2,2-trifluor-1-(trifluormethyl)ethyl>phosphinsaeureester (21223-05-2) + C16H11F6OP

Guidance literature:

In toluene; at 100 ℃; for 5h;

DOI:10.1002/1099-0682(200109)2001:9<2377::AID-EJIC2377>3.0.CO;2-3

upstream raw materials:

(2-TB-5-12)-3-methyl-2,2-diphenyl-4,4-bis-trifluoromethyl-2-(2,2,2-trifluoro-1-trifluoromethyl-ethoxy)-2λ⁵-[1,2]oxaphosphetane

bis-diphenylphosphinomethane

chloro-diphenylphosphine

2-ethyl-2,2-diphenyl-4,4,5,5-tetrakis-trifluoromethyl-2λ⁵-[1,3,2]dioxaphospholane