Phthalide, 4-benzamido- (5CI)

Base Information

• Chemical Name: Phthalide, 4-benzamido- (5CI)
• CAS No.: 705281-78-3
• Molecular Formula: C₁₅H₁₁NO₃
• Molecular Weight: 253.257
• Mol file: 705281-78-3.mol

Synonyms:Phthalide,4-benzamido- (5CI)

Chemical Property of Phthalide, 4-benzamido- (5CI)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Phthalide, 4-benzamido- (5CI)

There total 5 articles about Phthalide, 4-benzamido- (5CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-Amino-1(3H)-isobenzofuranon (59434-19-4) + benzoyl chloride (98-88-4) → 4-benzoylamino-phthalide (705281-78-3)

Guidance literature:

With sodium carbonate;

Reference yield:

2-benzofuran-1(3H)-one (87-41-2) → 4-benzoylamino-phthalide (705281-78-3)

Guidance literature:

Multi-step reaction with 3 steps

1: sulfuric acid; potassium nitrate

2: tin (II)-chloride; aqueous hydrochloric acid / Behandeln des Reaktionsprodukts mit wss. Natronlauge

3: aqueous sodium carbonate-solution

With hydrogenchloride; sulfuric acid; sodium carbonate; potassium nitrate; tin(ll) chloride;

Reference yield:

3-acetylaminophthalic anhydride (6296-53-3) → 4-benzoylamino-phthalide (705281-78-3)

Guidance literature:

Multi-step reaction with 3 steps

1: acetic acid anhydride; acetic acid; zinc-powder / Reagens 4: wss. Salzsaeure

2: ethanolic KOH-solution / Erhitzen des Reaktionsprodukts mit wss. Salzsaeure

3: aqueous sodium carbonate-solution

With potassium hydroxide; acetic anhydride; sodium carbonate; acetic acid; zinc;

upstream raw materials:

4-Amino-1(3H)-isobenzofuranon

benzoyl chloride

2-benzofuran-1(3H)-one

3-acetylaminophthalic anhydride