(2,5-dichloro-N-(4-nitronaphthalen-1-yl)benzenesulfonamide)

Base Information

• Chemical Name: (2,5-dichloro-N-(4-nitronaphthalen-1-yl)benzenesulfonamide)
• CAS No.: 52078-12-3
• Molecular Formula: C₁₆H₁₀Cl₂N₂O₄S
• Molecular Weight: 397.238
• Mol file: 52078-12-3.mol

Synonyms:(2,5-dichloro-N-(4-nitronaphthalen-1-yl)benzenesulfonamide)

Chemical Property of (2,5-dichloro-N-(4-nitronaphthalen-1-yl)benzenesulfonamide)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2,5-dichloro-N-(4-nitronaphthalen-1-yl)benzenesulfonamide)

There total 2 articles about (2,5-dichloro-N-(4-nitronaphthalen-1-yl)benzenesulfonamide) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

1-amino-4-nitronaphthalene (776-34-1) + 2,5-dichlorobenzenesulphonyl chloride (5402-73-3) → (2,5-dichloro-N-(4-nitronaphthalen-1-yl)benzenesulfonamide) (52078-12-3)

Guidance literature:

1-amino-4-nitronaphthalene; With sodium hydride; In tetrahydrofuran; mineral oil; at 0 ℃; for 0.166667h;

2,5-dichlorobenzenesulphonyl chloride; In tetrahydrofuran; mineral oil; at 25 ℃; for 12h;

DOI:10.1016/j.bmcl.2015.07.040

Reference yield:

→ (2,5-dichloro-N-(4-nitronaphthalen-1-yl)benzenesulfonamide) (52078-12-3)

Guidance literature:

aus 2,5-Dichlorbenzolsulfonylchlorid, 1-Amino-4-nitronaphthalin;

DOI:10.1021/jf60192a044

Reference yield: 68.0%

(2,5-dichloro-N-(4-nitronaphthalen-1-yl)benzenesulfonamide) (52078-12-3) + methyl iodide (74-88-4) → 2,5-dichloro-N-methyl-N-(4-nitronaphthalen-1-yl)benzenesulfonamide

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 25 ℃; for 20h;

DOI:10.1021/acs.jmedchem.9b01685

upstream raw materials:

1-amino-4-nitronaphthalene

2,5-dichlorobenzenesulphonyl chloride