methyl 4,4-bis-(3-phenyl-3,4-dihydro-2H-1,3-benzoxazin-6-yl)pentanoate

Base Information

• Chemical Name: methyl 4,4-bis-(3-phenyl-3,4-dihydro-2H-1,3-benzoxazin-6-yl)pentanoate
• CAS No.: 1268022-10-1
• Molecular Formula: C₃₄H₃₄N₂O₄
• Molecular Weight: 534.655
• Mol file: 1268022-10-1.mol

Synonyms:methyl 4,4-bis-(3-phenyl-3,4-dihydro-2H-1,3-benzoxazin-6-yl)pentanoate

Chemical Property of methyl 4,4-bis-(3-phenyl-3,4-dihydro-2H-1,3-benzoxazin-6-yl)pentanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 4,4-bis-(3-phenyl-3,4-dihydro-2H-1,3-benzoxazin-6-yl)pentanoate

There total 3 articles about methyl 4,4-bis-(3-phenyl-3,4-dihydro-2H-1,3-benzoxazin-6-yl)pentanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 4-hydroxy-γ-(4-hydroxyphenyl)-γ-methyl-benzenebutanoic acid methyl ester (7297-85-0) + 1,3,5-triphenylhexahydro-1,3,5-triazine (91-78-1) → methyl 4,4-bis-(3-phenyl-3,4-dihydro-2H-1,3-benzoxazin-6-yl)pentanoate (1268022-10-1)

Guidance literature:

In toluene; at 110 ℃; for 20h;

DOI:10.1002/pola.24541

Reference yield: 93.0%

4-hydroxy-γ-(4-hydroxyphenyl)-γ-methyl-benzenebutanoic acid methyl ester (7297-85-0) + 1,3,5-triphenylhexahydro-1,3,5-triazine (91-78-1) → methyl 4,4-bis-(3-phenyl-3,4-dihydro-2H-1,3-benzoxazin-6-yl)pentanoate (1268022-10-1)

Guidance literature:

With formaldehyd; In toluene; at 110 ℃; for 20h;

DOI:10.1039/c4ta00217b

Reference yield:

4,4-bis(4-hydroxyphenyl)valeric acid (126-00-1) → methyl 4,4-bis-(3-phenyl-3,4-dihydro-2H-1,3-benzoxazin-6-yl)pentanoate (1268022-10-1)

Guidance literature:

Multi-step reaction with 2 steps

1: toluene-4-sulfonic acid; trimethyl orthoformate / 16 h / Reflux

2: toluene / 20 h / 110 °C

With toluene-4-sulfonic acid; trimethyl orthoformate; In toluene;

DOI:10.1016/j.polymer.2016.05.053

upstream raw materials:

formaldehyd

4-hydroxy-γ-(4-hydroxyphenyl)-γ-methyl-benzenebutanoic acid methyl ester

1,3,5-triphenylhexahydro-1,3,5-triazine

4,4-bis(4-hydroxyphenyl)valeric acid