(1R,3S)-3-((tert-butyldiphenylsilyloxy)methyl)-1,2,2-trimethylcyclopentanecarbaldehyde

Base Information

Chemical Name:(1R,3S)-3-((tert-butyldiphenylsilyloxy)methyl)-1,2,2-trimethylcyclopentanecarbaldehyde
CAS No.:220272-31-1
Molecular Formula:C₂₆H₃₆O₂Si
Molecular Weight:408.656
Hs Code.:

Synonyms:(1R,3S)-3-((tert-butyldiphenylsilyloxy)methyl)-1,2,2-trimethylcyclopentanecarbaldehyde

Suppliers and Price of (1R,3S)-3-((tert-butyldiphenylsilyloxy)methyl)-1,2,2-trimethylcyclopentanecarbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1R,3S)-3-((tert-butyldiphenylsilyloxy)methyl)-1,2,2-trimethylcyclopentanecarbaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1R,3S)-3-((tert-butyldiphenylsilyloxy)methyl)-1,2,2-trimethylcyclopentanecarbaldehyde

There total 2 articles about (1R,3S)-3-((tert-butyldiphenylsilyloxy)methyl)-1,2,2-trimethylcyclopentanecarbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 220272-30-0
((1R,3S)-3-(((tert-butyldiphenylsilyl)oxy)methyl)-1,2,2-trimethylcyclopentyl)methanol

: 220272-31-1
(1R,3S)-3-((tert-butyldiphenylsilyloxy)methyl)-1,2,2-trimethylcyclopentanecarbaldehyde

Guidance literature:: With 4-methyl-morpholine; tetrapropylammonium perruthennate; In dichloromethane; at 20 ℃; for 4h; Molecular sieve;

Reference yield:

: 68510-42-9
(+)-(1R,3S)-1,2,2-Trimethyl-1,3-bis(hydroxymethyl)cyclopentane

: 220272-31-1
(1R,3S)-3-((tert-butyldiphenylsilyloxy)methyl)-1,2,2-trimethylcyclopentanecarbaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: 1H-imidazole / dichloromethane / 0 °C / Inert atmosphere

2: triethylamine; sulfur trioxide pyridine complex / dichloromethane; dimethyl sulfoxide / 2 h / 0 °C / Inert atmosphere

With 1H-imidazole; sulfur trioxide pyridine complex; triethylamine; In dichloromethane; dimethyl sulfoxide;
DOI:10.3390/molecules26061629

Reference yield: 82.0%

: 7677-24-9
trimethylsilyl cyanide

: 220272-31-1
(1R,3S)-3-((tert-butyldiphenylsilyloxy)methyl)-1,2,2-trimethylcyclopentanecarbaldehyde

: 501-53-1,94274-21-2
benzyl chloroformate

: 1188429-24-4
benzyl((1R,3S)-3-((tert-butyldiphenylsilyloxy)methyl)-1,2,2-trimethyl-cyclopentyl)(cyano) ethylcarbamate

Guidance literature:: trimethylsilyl cyanide; (1R,3S)-3-((tert-butyldiphenylsilyloxy)methyl)-1,2,2-trimethylcyclopentanecarbaldehyde; zinc(II) iodide; at 20 ℃; for 0.25h;

With ammonia; In methanol; at 20 ℃; for 17h;

benzyl chloroformate; With sodium carbonate; In dichloromethane; water; at 20 ℃; for 3h;