Benzyl 2-(3-hydroxypropyl)pyrrolidine-1-carboxylate

Base Information

Chemical Name:Benzyl 2-(3-hydroxypropyl)pyrrolidine-1-carboxylate
CAS No.:1026417-23-1
Molecular Formula:C₁₅H₂₁NO₃
Molecular Weight:263.337
Hs Code.:
DSSTox Substance ID:DTXSID701197883

Synonyms:Benzyl 2-(3-hydroxypropyl)pyrrolidine-1-carboxylate;1026417-23-1;DTXSID701197883;AKOS011757233;CS-0293168;EN300-6958707;Phenylmethyl 2-(3-hydroxypropyl)-1-pyrrolidinecarboxylate

Suppliers and Price of Benzyl 2-(3-hydroxypropyl)pyrrolidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Benzyl 2-(3-hydroxypropyl)pyrrolidine-1-carboxylate

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:263.15214353
Heavy Atom Count:19
Complexity:277

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CC(N(C1)C(=O)OCC2=CC=CC=C2)CCCO

Technology Process of Benzyl 2-(3-hydroxypropyl)pyrrolidine-1-carboxylate

There total 3 articles about Benzyl 2-(3-hydroxypropyl)pyrrolidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 7699-50-5
(+/-)-3-(2-pyrrolidinyl)-1-propanol

: 501-53-1,94274-21-2
benzyl chloroformate

: 1026417-23-1
2-(3-Hydroxy-propyl)-pyrrolidine-1-carboxylic acid benzyl ester

Guidance literature:: With sodium hydrogencarbonate; In water; for 1.5h; Ambient temperature;
DOI:10.1002/jhet.5570350219

Reference yield:

: 3-Pyrrolidin-(2Z)-ylidene-dihydro-furan-2-one

: 1026417-23-1
2-(3-Hydroxy-propyl)-pyrrolidine-1-carboxylic acid benzyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 90 percent / 3N aq. HCl / 12 h / 60 °C

2: 90 percent / NaBH₄ / ethanol / 48 h

3: 65 percent / NaHCO₃ / H₂O / 1.5 h / Ambient temperature

With hydrogenchloride; sodium tetrahydroborate; sodium hydrogencarbonate; In ethanol; water;
DOI:10.1002/jhet.5570350219

Reference yield:

: 209409-18-7
3-(3,4-dihydro-2H-pyrrol-5-yl)propan-1-ol

: 1026417-23-1
2-(3-Hydroxy-propyl)-pyrrolidine-1-carboxylic acid benzyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / NaBH₄ / ethanol / 48 h

2: 65 percent / NaHCO₃ / H₂O / 1.5 h / Ambient temperature

With sodium tetrahydroborate; sodium hydrogencarbonate; In ethanol; water;
DOI:10.1002/jhet.5570350219