(alphaS,betaS)-beta-Amino-alpha-[(phenylmethoxy)methyl]benzenepropanol

Base Information

Chemical Name:(alphaS,betaS)-beta-Amino-alpha-[(phenylmethoxy)methyl]benzenepropanol
CAS No.:1053517-88-6
Molecular Formula:C₁₇H₂₁NO₂
Molecular Weight:271.359
Hs Code.:
DSSTox Substance ID:DTXSID401201512

Synonyms:DTXSID401201512;(alphaS,betaS)-beta-Amino-alpha-[(phenylmethoxy)methyl]benzenepropanol;1053517-88-6

Suppliers and Price of (alphaS,betaS)-beta-Amino-alpha-[(phenylmethoxy)methyl]benzenepropanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of (alphaS,betaS)-beta-Amino-alpha-[(phenylmethoxy)methyl]benzenepropanol

Chemical Property:

XLogP3:2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:7
Exact Mass:271.157228913
Heavy Atom Count:20
Complexity:247

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)CC(C(COCC2=CC=CC=C2)O)N
Isomeric SMILES:C1=CC=C(C=C1)C[C@@H]([C@@H](COCC2=CC=CC=C2)O)N

Technology Process of (alphaS,betaS)-beta-Amino-alpha-[(phenylmethoxy)methyl]benzenepropanol

There total 1 articles about (alphaS,betaS)-beta-Amino-alpha-[(phenylmethoxy)methyl]benzenepropanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 193953-56-9
(4S,5S)-4-benzyl-5-benzyloxymethyl-1,3-oxazolidin-2-one

: 1053517-88-6
(2S,3S)-3-Amino-1-benzyloxy-4-phenyl-butan-2-ol

Guidance literature:: With potassium hydroxide; In ethanol; at 70 ℃; for 3h;
DOI:10.1021/jo9706943

Reference yield:

: 1053517-88-6
(2S,3S)-3-Amino-1-benzyloxy-4-phenyl-butan-2-ol

: 98760-08-8,98818-34-9,98818-35-0,103127-56-6,98737-29-2
(1-oxiranyl-2-phenylethyl)carbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: CH₂Cl₂ / 3 h / 23 °C

2: 356 mg / H₂ / Pd(OH)2 / ethyl acetate; methanol / 12 h

3: 61 percent / PPh₃, DEAD / CHCl₃ / 72 h / Heating

With hydrogen; triphenylphosphine; diethylazodicarboxylate; palladium dihydroxide; In methanol; dichloromethane; chloroform; ethyl acetate;
DOI:10.1021/jo980159i

Reference yield:

: 1053517-88-6
(2S,3S)-3-Amino-1-benzyloxy-4-phenyl-butan-2-ol

: 160232-08-6
(2R,3S)-3-tert-butoxycarbonylamino-1-isobutylamino-4-phenyl-2-butanol

Guidance literature:: Multi-step reaction with 4 steps

1: CH₂Cl₂ / 3 h / 23 °C

2: 356 mg / H₂ / Pd(OH)2 / ethyl acetate; methanol / 12 h

3: 61 percent / PPh₃, DEAD / CHCl₃ / 72 h / Heating

4: propan-2-ol / 3.5 h / 68 °C

With hydrogen; triphenylphosphine; diethylazodicarboxylate; palladium dihydroxide; In methanol; dichloromethane; chloroform; ethyl acetate; isopropyl alcohol;
DOI:10.1021/jo980159i