Technology Process of (E)-N-(2, 6-dimethylphenyl)-2,3-diphenylacrylamide
There total 4 articles about (E)-N-(2, 6-dimethylphenyl)-2,3-diphenylacrylamide which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
palladium diacetate; potassium carbonate; 1,3-bis[2,6-diisopropylphenyl]imidazolium chloride;
In
dichloromethane;
at 60 ℃;
for 2h;
Schlenk technique;
Inert atmosphere;
DOI:10.1021/acs.joc.0c02700
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: n-butyllithium / tetrahydrofuran / 4 h / -78 °C / Schlenk technique
1.2: 0.17 h / Schlenk technique; Inert atmosphere
2.1: 1,3-bis[2,6-diisopropylphenyl]imidazolium chloride; potassium carbonate; palladium diacetate / dichloromethane / 2 h / 60 °C / Schlenk technique; Inert atmosphere
With
n-butyllithium; palladium diacetate; potassium carbonate; 1,3-bis[2,6-diisopropylphenyl]imidazolium chloride;
In
tetrahydrofuran; dichloromethane;
DOI:10.1021/acs.joc.0c02700
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 1,3-bis[2,6-diisopropylphenyl]imidazolium chloride; potassium carbonate; palladium diacetate / 2 h / 60 °C / Schlenk technique; Inert atmosphere
2.1: n-butyllithium / tetrahydrofuran / 4 h / -78 °C / Schlenk technique
2.2: 0.17 h / Schlenk technique; Inert atmosphere
3.1: 1,3-bis[2,6-diisopropylphenyl]imidazolium chloride; potassium carbonate; palladium diacetate / dichloromethane / 2 h / 60 °C / Schlenk technique; Inert atmosphere
With
n-butyllithium; palladium diacetate; potassium carbonate; 1,3-bis[2,6-diisopropylphenyl]imidazolium chloride;
In
tetrahydrofuran; dichloromethane;
DOI:10.1021/acs.joc.0c02700
