[1,1,1-⁽²⁾H₃]-4-(benzyloxy)-2-butanone

Base Information

• Chemical Name: [1,1,1-⁽²⁾H₃]-4-(benzyloxy)-2-butanone
• CAS No.: 858970-91-9
• Molecular Formula: C₁₁H₁₄O₂
• Molecular Weight: 181.207
• Mol file: 858970-91-9.mol

Synonyms:[1,1,1-⁽²⁾H₃]-4-(benzyloxy)-2-butanone

Chemical Property of [1,1,1-⁽²⁾H₃]-4-(benzyloxy)-2-butanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [1,1,1-⁽²⁾H₃]-4-(benzyloxy)-2-butanone

There total 4 articles about [1,1,1-⁽²⁾H₃]-4-(benzyloxy)-2-butanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

[1,1,1-(2)H3]-4-(benzyloxy)-2-butanol (858970-90-8) → [1,1,1-(2)H3]-4-(benzyloxy)-2-butanone (858970-91-9)

Guidance literature:

With pyridinium chlorochromate; In dichloromethane;

DOI:10.1021/jo050449g

Reference yield:

3-benzyloxypropan-1-ol (4799-68-2) → [1,1,1-(2)H3]-4-(benzyloxy)-2-butanone (858970-91-9)

Guidance literature:

Multi-step reaction with 3 steps

1.1: 78 percent / pyridinium chlorochromate / CH₂Cl₂

2.1: Mg / diethyl ether

2.2: 90 percent / diethyl ether / 20 °C

3.1: 93 percent / pyridinium chlorochromate / CH₂Cl₂

With magnesium; pyridinium chlorochromate; In diethyl ether; dichloromethane;

DOI:10.1021/jo050449g

Reference yield:

3-Benzyloxypropanal (19790-60-4) → [1,1,1-(2)H3]-4-(benzyloxy)-2-butanone (858970-91-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: Mg / diethyl ether

1.2: 90 percent / diethyl ether / 20 °C

2.1: 93 percent / pyridinium chlorochromate / CH₂Cl₂

With magnesium; pyridinium chlorochromate; In diethyl ether; dichloromethane;

DOI:10.1021/jo050449g

upstream raw materials:

[1,1,1-⁽²⁾H₃]-4-(benzyloxy)-2-butanol

3-benzyloxypropan-1-ol

3-Benzyloxypropanal

benzyl bromide

Downstream raw materials:

[1,1,1,3,3-⁽²⁾H₅]-4-(benzyloxy)-2-butanone

ethyl [4,4,6,6,6-⁽²⁾H₅]-5-(benzyloxy)-3-hydroxy-3-methylpentanoate