(2R,4S)-4-amino-5-biphenyl-4-yl-2-methylpentanoic acid benzyl ester hydrochloride

Base Information

Chemical Name:(2R,4S)-4-amino-5-biphenyl-4-yl-2-methylpentanoic acid benzyl ester hydrochloride
CAS No.:1257265-27-2
Molecular Formula:C₂₅H₂₇NO₂*ClH
Molecular Weight:409.956
Hs Code.:

Synonyms:(2R,4S)-4-amino-5-biphenyl-4-yl-2-methylpentanoic acid benzyl ester hydrochloride

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Chemical Property of (2R,4S)-4-amino-5-biphenyl-4-yl-2-methylpentanoic acid benzyl ester hydrochloride

Chemical Property:

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Technology Process of (2R,4S)-4-amino-5-biphenyl-4-yl-2-methylpentanoic acid benzyl ester hydrochloride

There total 2 articles about (2R,4S)-4-amino-5-biphenyl-4-yl-2-methylpentanoic acid benzyl ester hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1257266-74-2
(2R,4S)-5-biphenyl-4-yl-4-tert-butoxycarbonylamino-2-methyl-pentanoic acid benzyl ester

: 1257265-27-2
(2R,4S)-4-amino-5-biphenyl-4-yl-2-methylpentanoic acid benzyl ester hydrochloride

Guidance literature:: With hydrogenchloride; In tetrahydrofuran; 1,4-dioxane; at 20 ℃; for 1h;

Reference yield:

: 1012341-50-2,1012341-54-6
(2R,4S)-5-[(1,1‘-biphenyl)-4-yl]-4-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid

: 1257266-74-2
(2R,4S)-5-biphenyl-4-yl-4-tert-butoxycarbonylamino-2-methyl-pentanoic acid benzyl ester

: 1257265-27-2
(2R,4S)-4-amino-5-biphenyl-4-yl-2-methylpentanoic acid benzyl ester hydrochloride

Guidance literature:: With hydrogenchloride; potassium carbonate; In tetrahydrofuran; 1,4-dioxane; n-heptane; water; benzyl bromide; ethyl acetate; N,N-dimethyl-formamide;

Reference yield:

: 99-32-1
chelidonic acid

: 1257265-27-2
(2R,4S)-4-amino-5-biphenyl-4-yl-2-methylpentanoic acid benzyl ester hydrochloride

: 1257265-30-7
6-((1S,3R)-3-benzyloxycarbonyl-1-biphenyl-4-ylmethylbutylcarbamoyl)-4-oxo-4H-pyran-2-carboxylic acid

Guidance literature:: chelidonic acid; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 ℃; for 0.166667h;

(2R,4S)-4-amino-5-biphenyl-4-yl-2-methylpentanoic acid benzyl ester hydrochloride; With triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 48h;