N-octanoylsphingosine

Base Information

Chemical Name:N-octanoylsphingosine
CAS No.:74713-59-0
Molecular Formula:C26H51 N O3
Molecular Weight:425.69
Hs Code.:29225000
DSSTox Substance ID:DTXSID701318293
Nikkaji Number:J640.421I
Wikidata:Q27120632
ChEMBL ID:CHEMBL444463
Mol file:74713-59-0.mol

Synonyms:2,3-N-octanoyl-D-erythro-trans-sphingosine;2,3-N-octanoylsphingosine;C8-ceramide

Suppliers and Price of N-octanoylsphingosine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
C8 Ceramide
5mg
$ 410.00

TRC
C-8Ceramide
1mg
$ 45.00

SynQuest Laboratories
C8 Ceramide
5 mg
$ 95.00

SynQuest Laboratories
C8 Ceramide
50 mg
$ 495.00

Medical Isotopes, Inc.
C8Ceramide
25 mg
$ 1480.00

Medical Isotopes, Inc.
C8Ceramide
5 mg
$ 810.00

ChemScene
C8-Ceramide ≥98.0%
5mg
$ 295.00

Cayman Chemical
C-8 Ceramide ≥98%
10mg
$ 87.00

Cayman Chemical
C-8 Ceramide ≥98%
5mg
$ 50.00

Cayman Chemical
C-8 Ceramide ≥98%
1mg
$ 12.00

Total 15 raw suppliers

Chemical Property of N-octanoylsphingosine

Chemical Property:

Appearance/Colour:Off White Powder
Vapor Pressure:1.16E-16mmHg at 25°C
Melting Point:68-70°C
Refractive Index:1.482
Boiling Point:595.5°C at 760 mmHg
Flash Point:313.9°C
PSA：69.56000
Density:0.939g/cm³
LogP:6.83310
Storage Temp.:−20°C
Solubility.:DMSO or ethanol: soluble
XLogP3:8.5
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:22
Exact Mass:425.38689449
Heavy Atom Count:30
Complexity:398

Purity/Quality:

97% ^*data from raw suppliers

C8 Ceramide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCCCCCCCCCCC=CC(C(CO)NC(=O)CCCCCCC)O
Isomeric SMILES:CCCCCCCCCCCCC/C=C/[C@H]([C@H](CO)NC(=O)CCCCCCC)O
Description C8-ceramide (74713-59-0) is a cell permeable ceramide analog. Stimulates ceramide-activated protein kinase.1?Induces apoptosis.2?Reported to inhibit apoptosis and gap junction intercellular communication (GJIC) in rat liver epithelial cells.3?C8-ceramide induces the secretion of brain-derived neurotrophic factor (BDNF) from microglia?in vitro.4
Uses A biologically active, cell permeable, but nonphysiologic ceramide analog. It induces phosphorylation on Thr-669 in A-431 cells by stimulation of ceramide-activated protein kinase. It stimulates IL-2 secretion and induces apoptosis C-8 Ceramide is a ceramide analog.

Technology Process of N-octanoylsphingosine

There total 4 articles about N-octanoylsphingosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

: 74713-59-0,175892-44-1
N-octanoylsphingosine

Guidance literature:: With benzotriazol-1-ol; dicyclohexyl-carbodiimide; In tetrahydrofuran; at 20 ℃;

Reference yield:

: 123-78-4
(2S,3R,4E)-2-amino-4-octadecene-1,3-diol

: 111-64-8
n-octanoic acid chloride

: 74713-59-0,175892-44-1
N-octanoylsphingosine

Guidance literature:: n-octanoic acid chloride; With pyridine; In 1-methyl-pyrrolidin-2-one; at 20 ℃;

(2S,3R,4E)-2-amino-4-octadecene-1,3-diol; In tetrahydrofuran; at 20 ℃; Further stages.;
DOI:10.1021/ja017576o