Technology Process of (R)-(-)-1-(3,4-dimethoxyphenyl)-2-(isopropylamino)ethanol
There total 8 articles about (R)-(-)-1-(3,4-dimethoxyphenyl)-2-(isopropylamino)ethanol which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
(R)-(-)-2-amino-1-(3,4-dimethoxyphenyl)ethanol; acetone;
In
ethanol;
at 25 ℃;
for 1h;
With
sodium tetrahydroborate;
In
ethanol;
at 25 ℃;
for 1h;
DOI:10.1039/c8nj01745j
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 97 percent / potassium ferricyanide; potassium carbonate; osmium tetroxide / (DHQD)2PHAL / H2O; 2-methyl-propan-2-ol; toluene / 24 h / 0 °C
2: 95 percent / dibutyltin oxide; triethylamine / CH2Cl2 / 0.75 h / 20 °C
3: 95 percent / sodium iodide / acetone / 6 h / Heating
4: 7 h / 80 °C
With
osmium(VIII) oxide; di(n-butyl)tin oxide; potassium carbonate; triethylamine; sodium iodide; potassium hexacyanoferrate(III);
1,4-bis(9-O-dihydroquinidine)phthalazine;
In
dichloromethane; water; acetone; toluene; tert-butyl alcohol;
1: Sharpless asymmetric dihydroxylation;
DOI:10.1016/j.tetasy.2004.11.005
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 95 percent / dibutyltin oxide; triethylamine / CH2Cl2 / 0.75 h / 20 °C
2: 95 percent / sodium iodide / acetone / 6 h / Heating
3: 7 h / 80 °C
With
di(n-butyl)tin oxide; triethylamine; sodium iodide;
In
dichloromethane; acetone;
DOI:10.1016/j.tetasy.2004.11.005
