(2S,3R,4S,5S,6R)-2-(4-chloro-3-((5-(furan-2-yl)thiazol-2-yl)methyl)phenyl)-6-methyl-tetrahydro-2H-pyran-3,4,5-triol

Base Information

Chemical Name:(2S,3R,4S,5S,6R)-2-(4-chloro-3-((5-(furan-2-yl)thiazol-2-yl)methyl)phenyl)-6-methyl-tetrahydro-2H-pyran-3,4,5-triol
CAS No.:1270018-33-1
Molecular Formula:C₂₀H₂₀ClNO₅S
Molecular Weight:421.901
Hs Code.:

Synonyms:(2S,3R,4S,5S,6R)-2-(4-chloro-3-((5-(furan-2-yl)thiazol-2-yl)methyl)phenyl)-6-methyl-tetrahydro-2H-pyran-3,4,5-triol

Suppliers and Price of (2S,3R,4S,5S,6R)-2-(4-chloro-3-((5-(furan-2-yl)thiazol-2-yl)methyl)phenyl)-6-methyl-tetrahydro-2H-pyran-3,4,5-triol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,3R,4S,5S,6R)-2-(4-chloro-3-((5-(furan-2-yl)thiazol-2-yl)methyl)phenyl)-6-methyl-tetrahydro-2H-pyran-3,4,5-triol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,3R,4S,5S,6R)-2-(4-chloro-3-((5-(furan-2-yl)thiazol-2-yl)methyl)phenyl)-6-methyl-tetrahydro-2H-pyran-3,4,5-triol

There total 3 articles about (2S,3R,4S,5S,6R)-2-(4-chloro-3-((5-(furan-2-yl)thiazol-2-yl)methyl)phenyl)-6-methyl-tetrahydro-2H-pyran-3,4,5-triol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 31.0%

: 1270018-23-9
(2S,3R,4R,5S,6S)-2-(4-chloro-3-((5-(furan-2-yl)thiazol-2-yl)methyl)phenyl)-6-(iodomethyl)-tetrahydro-2H-pyran-3,4,5-triol

: 1270018-33-1
(2S,3R,4S,5S,6R)-2-(4-chloro-3-((5-(furan-2-yl)thiazol-2-yl)methyl)phenyl)-6-methyl-tetrahydro-2H-pyran-3,4,5-triol

Guidance literature:: With hydrogen; In methanol; diethylamine; at 20 ℃; for 24h;
DOI:10.1016/j.bmcl.2010.11.115

Reference yield:

: 1260242-23-6
(2S,3R,4R,5S,6R)-2-(4-chloro-3-((5-(furan-2-yl)thiazol-2-yl)methyl)phenyl)-6-(hydroxymethyl)-tetrahydro-2H-pyran-3,4,5-triol

: 1270018-33-1
(2S,3R,4S,5S,6R)-2-(4-chloro-3-((5-(furan-2-yl)thiazol-2-yl)methyl)phenyl)-6-methyl-tetrahydro-2H-pyran-3,4,5-triol

Guidance literature:: Multi-step reaction with 3 steps

1: 2,6-dimethylpyridine / 15 h / 20 °C

2: sodium iodide / butanone / 2 h / 80 °C

3: hydrogen / methanol; diethylamine / 24 h / 20 °C

With 2,6-dimethylpyridine; hydrogen; sodium iodide; In methanol; diethylamine; butanone;
DOI:10.1016/j.bmcl.2010.11.115

Reference yield:

: 1270018-18-2
((2R,3S,4R,5R,6S)-6-(4-chloro-3-((5-(furan-2-yl)thiazol-2-yl)methyl)phenyl)-3,4,5-trihydroxy-tetrahydro-2H-pyran-2-yl)methyl 4-methylbenzenesulfonate

: 1270018-33-1
(2S,3R,4S,5S,6R)-2-(4-chloro-3-((5-(furan-2-yl)thiazol-2-yl)methyl)phenyl)-6-methyl-tetrahydro-2H-pyran-3,4,5-triol

Guidance literature:: Multi-step reaction with 2 steps

1: sodium iodide / butanone / 2 h / 80 °C / Inert atmosphere

2: diethylamine; hydrogen / Raney nickel / methanol / 24 h / 760.05 Torr

With hydrogen; diethylamine; sodium iodide; Raney nickel; In methanol; butanone;