(R,Z)-2-(3-((2-carboxy-N-(4-((4-oxo-2-thioxothiazolidin-5-ylidene)methyl)phenyl)acetamido)methyl)benzamido)pentanedioic acid

Base Information

Chemical Name:(R,Z)-2-(3-((2-carboxy-N-(4-((4-oxo-2-thioxothiazolidin-5-ylidene)methyl)phenyl)acetamido)methyl)benzamido)pentanedioic acid
CAS No.:1310744-99-0
Molecular Formula:C₂₆H₂₃N₃O₉S₂
Molecular Weight:585.615
Hs Code.:

Synonyms:(R,Z)-2-(3-((2-carboxy-N-(4-((4-oxo-2-thioxothiazolidin-5-ylidene)methyl)phenyl)acetamido)methyl)benzamido)pentanedioic acid

Suppliers and Price of (R,Z)-2-(3-((2-carboxy-N-(4-((4-oxo-2-thioxothiazolidin-5-ylidene)methyl)phenyl)acetamido)methyl)benzamido)pentanedioic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (R,Z)-2-(3-((2-carboxy-N-(4-((4-oxo-2-thioxothiazolidin-5-ylidene)methyl)phenyl)acetamido)methyl)benzamido)pentanedioic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R,Z)-2-(3-((2-carboxy-N-(4-((4-oxo-2-thioxothiazolidin-5-ylidene)methyl)phenyl)acetamido)methyl)benzamido)pentanedioic acid

There total 7 articles about (R,Z)-2-(3-((2-carboxy-N-(4-((4-oxo-2-thioxothiazolidin-5-ylidene)methyl)phenyl)acetamido)methyl)benzamido)pentanedioic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 1310744-93-4
(R,Z)-dimethyl 2-(3-((3-methoxy-3-oxo-N-(4-((4-oxo-2-thioxothiazolidin-5-ylidene)methyl)phenyl)propanamido)methyl)benzamido)pentanedioate

: 1310744-99-0
(R,Z)-2-(3-((2-carboxy-N-(4-((4-oxo-2-thioxothiazolidin-5-ylidene)methyl)phenyl)acetamido)methyl)benzamido)pentanedioic acid

Guidance literature:: (R,Z)-dimethyl 2-(3-((3-methoxy-3-oxo-N-(4-((4-oxo-2-thioxothiazolidin-5-ylidene)methyl)phenyl)propanamido)methyl)benzamido)pentanedioate; With lithium hydroxide; In methanol; water; at 20 ℃; for 16h;

With hydrogenchloride; In methanol; water;
DOI:10.1021/jm2002525

Reference yield:

: 1243277-48-6
(R,Z)-dimethyl 2-(3-(((4-((4-oxo-2-thioxothiazolidin-5-ylidene)methyl)phenyl)amino)methyl)benzamido)pentanedioate

: 1310744-99-0
(R,Z)-2-(3-((2-carboxy-N-(4-((4-oxo-2-thioxothiazolidin-5-ylidene)methyl)phenyl)acetamido)methyl)benzamido)pentanedioic acid

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / 24 h / 0 - 20 °C

2: lithium hydroxide / methanol; water / 16 h / 20 °C

With triethylamine; lithium hydroxide; In methanol; water;
DOI:10.1021/jm2002525

Reference yield:

: 99361-26-9
(5Z)-5-(4-aminobenzylidene)-2-thioxo-1,3-thiazolidin-4-one

: 1310744-99-0
(R,Z)-2-(3-((2-carboxy-N-(4-((4-oxo-2-thioxothiazolidin-5-ylidene)methyl)phenyl)acetamido)methyl)benzamido)pentanedioic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: acetic acid / methanol / 1 h / 65 °C

1.2: 20 h / 20 °C / Inert atmosphere

2.1: triethylamine / 24 h / 0 - 20 °C

3.1: lithium hydroxide / methanol; water / 16 h / 20 °C

With acetic acid; triethylamine; lithium hydroxide; In methanol; water;
DOI:10.1021/jm2002525