ethyl 5-(but-3'-en-1'-yl)-2-phenyl-1-pyrroline-5-carboxylate 1-oxide

Base Information

• Chemical Name: ethyl 5-(but-3'-en-1'-yl)-2-phenyl-1-pyrroline-5-carboxylate 1-oxide
• CAS No.: 212263-61-1
• Molecular Formula: C₁₇H₂₁NO₃
• Molecular Weight: 287.359
• Mol file: 212263-61-1.mol

Synonyms:ethyl 5-(but-3'-en-1'-yl)-2-phenyl-1-pyrroline-5-carboxylate 1-oxide

Chemical Property of ethyl 5-(but-3'-en-1'-yl)-2-phenyl-1-pyrroline-5-carboxylate 1-oxide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of ethyl 5-(but-3'-en-1'-yl)-2-phenyl-1-pyrroline-5-carboxylate 1-oxide

There total 1 articles about ethyl 5-(but-3'-en-1'-yl)-2-phenyl-1-pyrroline-5-carboxylate 1-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

ethyl 2-phenyl-1-pyrroline-5-carboxylate 1-oxide (212265-33-3) → ethyl 5-(but-3'-en-1'-yl)-2-phenyl-1-pyrroline-5-carboxylate 1-oxide (212263-61-1)

Guidance literature:

ethyl 2-phenyl-1-pyrroline-5-carboxylate 1-oxide; With sodium hydride; In tetrahydrofuran; N,N-dimethyl-formamide; at 20 ℃; for 0.0833333h;

CH₂=CH(CH₂)2X, X = halide; In tetrahydrofuran; N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1055/s-2006-942380

Reference yield: 51.0%

ethyl 5-(but-3'-en-1'-yl)-2-phenyl-1-pyrroline-5-carboxylate 1-oxide (212263-61-1) → ethyl cis-2-(but-3'-en-1'-yl)-5-phenyl-6-oxa-1-azabicyclo[3.1.0]hexane-2-carboxylate + ethyl trans-2-(but-3'-en-1'-yl)-5-phenyl-6-oxa-1-azabicyclo[3.1.0]hexane-2-carboxylate

Guidance literature:

In benzene; for 16h; UV-irradiation;

DOI:10.1055/s-2006-942380

Reference yield:

ethyl 5-(but-3'-en-1'-yl)-2-phenyl-1-pyrroline-5-carboxylate 1-oxide (212263-61-1) → ethyl 1-amino-4-hydroxy-6-phenylcyclooctane-1-carboxylate

Guidance literature:

Multi-step reaction with 2 steps

1: 28 percent / xylene / 48 h / Heating

2: 47 percent / H₂ / 10 percent Pd/C / ethanol / 72 h / 2068.59 Torr

With hydrogen; palladium on activated charcoal; In ethanol; xylene; 1: Cyclization / 2: Hydrogenolysis;

DOI:10.1006/bioo.1998.1123

upstream raw materials:

ethyl 2-phenyl-1-pyrroline-5-carboxylate 1-oxide

Downstream raw materials:

ethyl 5-(but-3'-en-1'-yl)-2-phenyl-1-pyrroline-5-carboxylate