Technology Process of 5-benzyloxy-1-<2-(3-bromo)-propyloxy>-ethoxypentane
There total 7 articles about 5-benzyloxy-1-<2-(3-bromo)-propyloxy>-ethoxypentane which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
carbon tetrabromide; triphenylphosphine;
In
dichloromethane;
at 0 ℃;
for 0.5h;
DOI:10.1139/v94-187
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 1.) NaH / 1.) THF, RT, 30 min, 2.) THF, reflux, overnight
2: 83 percent / 50percent NaOH, (Bu4N)HSO4 / 72 h / 65 °C
3: 91 percent / pyridinium p-toluenesulfonate / methanol / 12 h / Ambient temperature
4: 83 percent / 50percent NaOH, (Bu4N)HSO4 / 72 h / 65 °C
5: 89 percent / Bu4NF / tetrahydrofuran / 12 h / Ambient temperature
6: 88 percent / CBr4, PPh3 / CH2Cl2 / 0.5 h / 0 °C
With
sodium hydroxide; carbon tetrabromide; tetrabutyl ammonium fluoride; tetra(n-butyl)ammonium hydrogensulfate; pyridinium p-toluenesulfonate; sodium hydride; triphenylphosphine;
In
tetrahydrofuran; methanol; dichloromethane;
DOI:10.1139/v94-187
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 83 percent / 50percent NaOH, (Bu4N)HSO4 / 72 h / 65 °C
2: 91 percent / pyridinium p-toluenesulfonate / methanol / 12 h / Ambient temperature
3: 83 percent / 50percent NaOH, (Bu4N)HSO4 / 72 h / 65 °C
4: 89 percent / Bu4NF / tetrahydrofuran / 12 h / Ambient temperature
5: 88 percent / CBr4, PPh3 / CH2Cl2 / 0.5 h / 0 °C
With
sodium hydroxide; carbon tetrabromide; tetrabutyl ammonium fluoride; tetra(n-butyl)ammonium hydrogensulfate; pyridinium p-toluenesulfonate; triphenylphosphine;
In
tetrahydrofuran; methanol; dichloromethane;
DOI:10.1139/v94-187
