5-BENZYLOXY-1-PENTANOL

Base Information

• Chemical Name: 5-BENZYLOXY-1-PENTANOL
• CAS No.: 4541-15-5
• Molecular Formula: C12H18 O2
• Molecular Weight: 194.274
• Hs Code.: 2909499000
• Mol file: 4541-15-5.mol

Synonyms:1-Pentanol,5-(benzyloxy)- (7CI,8CI); 1,5-Pentanediol monobenzyl ether;5-(Benzyloxy)-1-pentanol; 5-(Phenylmethoxy)-1-pentanol; 5-Benzyloxypentanol;NSC 5422; Pentanediol benzyl ether

Chemical Property of 5-BENZYLOXY-1-PENTANOL

Chemical Property:

• Vapor Pressure: 0.000631mmHg at 25°C
• Refractive Index: n20/D 1.505(lit.)
• Boiling Point: 140 °C0.4 mm Hg(lit.)
• PKA: 15.15±0.10(Predicted)
• Flash Point: >230 °F
• PSA: 29.46000
• Density: 1.008 g/mL at 25 °C(lit.)
• LogP: 2.36580
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

5-Benzyloxypentanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 5-Benzyloxy-1-pentanol (5-(benzyloxy)pentan-1-ol) may be used as a starting material in the synthesis of 5-benzyloxypentanal and (±)tanikolide.

Technology Process of 5-BENZYLOXY-1-PENTANOL

There total 21 articles about 5-BENZYLOXY-1-PENTANOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

1 ,5-pentanediol (111-29-5) + benzyl bromide (100-39-0) → 5-(benzyloxy)-1-pentanol (4541-15-5)

Guidance literature:

1 ,5-pentanediol; With sodium hydride; In tetrahydrofuran; at 0 ℃; for 0.5h;

benzyl bromide; In tetrahydrofuran; at 20 ℃; for 20h; Further stages.;

DOI:10.1021/ja068047t

Reference yield: 98.0%

(5-benzyloxy-pentyloxy)-tert-butyl-dimethyl-silane → 5-(benzyloxy)-1-pentanol (4541-15-5)

Guidance literature:

With cerium(IV) triflate; In acetonitrile; at 20 ℃; for 2.5h;

DOI:10.1016/S0040-4039(02)01254-6

Reference yield: 95.0%

C31H32O2 (157730-92-2) → 5-(benzyloxy)-1-pentanol (4541-15-5)

Guidance literature:

C₃₁H₃₂O₂; With boron trichloride; In dichloromethane; at -30 ℃; for 0.5h;

With methanol; Further stages.;

DOI:10.1021/jo9913255

upstream raw materials:

tetrahydro-2-(benzyloxy)-2H-pyran

1 ,5-pentanediol

benzyl bromide

6-benzyloxy-1-hexene

Downstream raw materials:

5-benzyloxypentanoic acid methyl ester

5-benzyloxypentanoic acid

1-(benzyloxy)-5-bromopentane

((5-chloropentyloxy)methyl)benzene