4-(2-Amino-6-methyl-pyrimidin-4-ylamino)-benzoic acid

Base Information

Chemical Name:4-(2-Amino-6-methyl-pyrimidin-4-ylamino)-benzoic acid
CAS No.:91560-28-0
Molecular Formula:C₁₂H₁₂N₄O₂
Molecular Weight:244.253
Hs Code.:
DSSTox Substance ID:DTXSID701212277
Nikkaji Number:J1.394.590J
ChEMBL ID:CHEMBL1733939
Mol file:91560-28-0.mol

Synonyms:4-(2-Amino-6-methyl-pyrimidin-4-ylamino)-benzoic acid;91560-28-0;2-Amino-4-(p-carboxyanilino)-6-methylpyrimidine;4-[(2-amino-6-methylpyrimidin-4-yl)amino]benzoic acid;p-(2-Amino-6-methyl-4-pyrimidinylamino)benzoic acid;MLS001208862;CHEMBL1733939;SCHEMBL12240493;DTXSID701212277;HMS1676G02;HMS2840I11;AKOS000111527;SMR000503810;BB 0238491;BRD-K37408813-001-08-7;4-(2-Amino-6-methyl-pyrimidin-4-ylamino)-be nzoic acid;4-[(2-Amino-6-methyl-4-pyrimidinyl)amino]benzoic acid;4-[(2-Amino-6-methyl-4-pyrimidinyl)amino]benzoic acid #

Suppliers and Price of 4-(2-Amino-6-methyl-pyrimidin-4-ylamino)-benzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
4-(2-Amino-6-methyl-pyrimidin-4-ylamino)-benzoic acid
1g
$ 378.00

Total 4 raw suppliers

Chemical Property of 4-(2-Amino-6-methyl-pyrimidin-4-ylamino)-benzoic acid

Chemical Property:

Boiling Point:550.7±60.0 °C(Predicted)
PKA:4.09±0.10(Predicted)
Density:1.411±0.06 g/cm3(Predicted)
XLogP3:1.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:244.09602564
Heavy Atom Count:18
Complexity:292

Purity/Quality:

99% ^*data from raw suppliers

4-(2-Amino-6-methyl-pyrimidin-4-ylamino)-benzoic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC(=NC(=N1)N)NC2=CC=C(C=C2)C(=O)O

Technology Process of 4-(2-Amino-6-methyl-pyrimidin-4-ylamino)-benzoic acid

There total 5 articles about 4-(2-Amino-6-methyl-pyrimidin-4-ylamino)-benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 1281258-20-5
C₁₄H₁₆N₄O₂

: 91560-28-0
2-Amino-4-(p-carboxyanilino)-6-methylpyrimidine

Guidance literature:: With potassium hydroxide; In ethanol; at 20 ℃;
DOI:10.1021/jm4012627

Reference yield:

: 5600-21-5
2-amino-6-methyl-4-chloropyrimidine

: 91560-28-0
2-Amino-4-(p-carboxyanilino)-6-methylpyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride / ethanol / 2 h / Reflux

2: potassium hydroxide / ethanol / 20 °C

With hydrogenchloride; potassium hydroxide; In ethanol;
DOI:10.1021/jm4012627

Reference yield:

: 94-09-7
p-aminoethylbenzoate

: 91560-28-0
2-Amino-4-(p-carboxyanilino)-6-methylpyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride / ethanol / 2 h / Reflux

2: potassium hydroxide / ethanol / 20 °C

With hydrogenchloride; potassium hydroxide; In ethanol;
DOI:10.1021/jm4012627