3,4,5-Tris(benzyloxy)benzyl Alcohol

Base Information

• Chemical Name: 3,4,5-Tris(benzyloxy)benzyl Alcohol
• CAS No.: 79831-88-2
• Molecular Formula: C28H26O4
• Molecular Weight: 426.512
• Hs Code.: 2909499000
• DSSTox Substance ID: DTXSID50464951
• Nikkaji Number: J2.312.163H
• Wikidata: Q82290534
• Mol file: 79831-88-2.mol

Synonyms:3,4,5-Tris(benzyloxy)benzyl Alcohol;79831-88-2;[3,4,5-tris(phenylmethoxy)phenyl]methanol;(3,4,5-tris(benzyloxy)phenyl)methanol;[3,4,5-TRIS(BENZYLOXY)PHENYL]METHANOL;3,4,5-Tribenzyloxybenzyl Alcohol;4-phenoxyphenylacetylene;SCHEMBL4420078;DTXSID50464951;FWPHSYJOSSBILN-UHFFFAOYSA-N;3,4,5-tribenzyloxy benzyl alcohol;3,4,5-tribenzyloxy-benzyl alcohol;3,4,5-Trisbenzyloxybenzyl Alcohol;MFCD02093503;AKOS015839498;CS-0207637;T1840;T72953

Chemical Property of 3,4,5-Tris(benzyloxy)benzyl Alcohol

Chemical Property:

• Vapor Pressure: 2.47E-15mmHg at 25°C
• Melting Point: 107 °C
• Refractive Index: 1.624
• Boiling Point: 601.8 °C at 760 mmHg
• Flash Point: 317.8 °C
• PSA: 47.92000
• Density: 1.193 g/cm³
• LogP: 5.91590
• Storage Temp.: Refrigerator
• Solubility.: DMSO (Slightly), Methanol (Slightly)
• XLogP3: 5.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 10
• Exact Mass: 426.18310931
• Heavy Atom Count: 32
• Complexity: 462

Purity/Quality:

98%,99%, ^*data from raw suppliers

3,4,5-Tris(benzyloxy)benzyl Alcohol ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)COC2=CC(=CC(=C2OCC3=CC=CC=C3)OCC4=CC=CC=C4)CO
• Uses: 3,4,5-Tris(benzyloxy)benzyl Alcohol, can be used in the synthesis of chemical compounds such as Benserazide Impurity B (A611100).

Technology Process of 3,4,5-Tris(benzyloxy)benzyl Alcohol

There total 19 articles about 3,4,5-Tris(benzyloxy)benzyl Alcohol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

methyl 3,4,5-tris(benzyloxy)benzoate (70424-94-1) → 3,4,5-tribenzyloxybenzyl alcohol (79831-88-2)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 25 ℃; for 2h; Inert atmosphere;

DOI:10.1021/ja400639q

Reference yield: 95.0%

propyl 3,4,5-tris(benzyloxy)benzoate → 3,4,5-tribenzyloxybenzyl alcohol (79831-88-2)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃;

DOI:10.1021/ja060062a

Reference yield: 95.0%

3,4,5-tribenzyl-methyl gallate → 3,4,5-tribenzyloxybenzyl alcohol (79831-88-2)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 2h; Heating / reflux;

upstream raw materials:

methyl 3,4,5-tris(benzyloxy)benzoate

Propyl gallate

benzyl chloride

methyl galloate

Downstream raw materials:

(((5-(chloromethyl)benzene-1,2,3-triyl)tris(oxy))tris(methylene))tribenzene

ethyl (E)-3,4,5-tris(benzyloxy)cinnamate

(3S,4R)-[(1S)-1-(3,4,5-tribenzyloxyphenyl)-1-hydroxymethyl]-4-(3,4-methylenedioxybenzyl)dihydro-2(3H)-furanone

C₄₃H₃₆O₄