METHYL 3,4,5-TRIS(BENZYLOXY)BENZOATE

Base Information

• Chemical Name: METHYL 3,4,5-TRIS(BENZYLOXY)BENZOATE
• CAS No.: 70424-94-1
• Molecular Formula: C29H26 O5
• Molecular Weight: 454.522
• Mol file: 70424-94-1.mol

Synonyms:Benzoicacid, 3,4,5-tris(benzyloxy)-, methyl ester (6CI); Methyl3,4,5-tribenzyloxybenzoate; Methyl 3,4,5-tris(benzyloxy)benzoate; Methyltri-O-benzylgallate; NSC 525276

Chemical Property of METHYL 3,4,5-TRIS(BENZYLOXY)BENZOATE

Chemical Property:

• Vapor Pressure: 1.2E-13mmHg at 25°C
• Melting Point: 98oC
• Boiling Point: 584.5 °C at 760 mmHg
• Flash Point: 249.3 °C
• PSA: 53.99000
• Density: 1.191 g/cm³
• LogP: 6.21020
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility.: Acetone, Chloroform, Dichloromethane

Purity/Quality:

98%,99%, ^*data from raw suppliers

Methyl 3,4,5-Tris(benzyloxy)benzoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Intermediate in the production of Gallic Acid derivatives.

Technology Process of METHYL 3,4,5-TRIS(BENZYLOXY)BENZOATE

There total 9 articles about METHYL 3,4,5-TRIS(BENZYLOXY)BENZOATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methyl galloate (99-24-1) + benzyl chloride (100-44-7) → methyl 3,4,5-tris(benzyloxy)benzoate (70424-94-1)

Guidance literature:

methyl galloate; With potassium carbonate; potassium iodide; In acetone; at 20 ℃; for 0.333333h;

benzyl chloride; In acetone; for 20h; Reflux;

DOI:10.1002/chem.201200517

Reference yield: 100.0%

methyl galloate (99-24-1) + benzyl bromide (100-39-0) → methyl 3,4,5-tris(benzyloxy)benzoate (70424-94-1)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 120 ℃; for 7h;

Reference yield: 88.0%

methyl 3-(benzyloxy)-4,5-dihydroxybenzoate (79831-86-0) + benzyl chloride (100-44-7) → methyl 3,4,5-tris(benzyloxy)benzoate (70424-94-1)

Guidance literature:

With potassium carbonate; potassium iodide; In acetone; for 18h; Heating;

DOI:10.1039/P19810002016

upstream raw materials:

methyl galloate

benzyl chloride

benzyl bromide

methyl 3-(benzyloxy)-4,5-dihydroxybenzoate

Downstream raw materials:

3,4,5-tribenzyloxybenzoic acid

3,4,5-trisbenzyloxybenzoic acid hydrazide

3,4,5-tribenzyloxybenzyl alcohol

methyl 3,4,5-tris(benzyloxy)-2-bromobenzoate

Refernces

• 1、 Fan, Long,Liu, Kui,Yang, Zheng-yin. "A novel and reversible multifunction probe for Al3+and F? by fluorogenic and colorimetric method". . . Retrieved 2022/03/27.
• 2、 Imai, Haruka,Koyama, Ryo,Horino, Yoshikazu,Abe, Hitoshi. "Preparation of isodehydrodigallic acid using Ullmann condensation". . p. 298 - 301. Retrieved 2021/03/08.