1-(2-(4-(trifluoromethyl)phenyl)allyl)-1H-benzo[d]imidazole

Base Information

• Chemical Name: 1-(2-(4-(trifluoromethyl)phenyl)allyl)-1H-benzo[d]imidazole
• CAS No.: 1181811-67-5
• Molecular Formula: C₁₇H₁₃F₃N₂
• Molecular Weight: 302.299
• Mol file: 1181811-67-5.mol

Synonyms:1-(2-(4-(trifluoromethyl)phenyl)allyl)-1H-benzo[d]imidazole

Chemical Property of 1-(2-(4-(trifluoromethyl)phenyl)allyl)-1H-benzo[d]imidazole

Chemical Property:

Purity/Quality:

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Technology Process of 1-(2-(4-(trifluoromethyl)phenyl)allyl)-1H-benzo[d]imidazole

There total 1 articles about 1-(2-(4-(trifluoromethyl)phenyl)allyl)-1H-benzo[d]imidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

2-(1H-benzo[d]imidazol-1-yl)-1-(4-(trifluoromethyl)henyl)ethanone (1181811-73-3) + Methyltriphenylphosphonium bromide (1779-49-3) → 1-(2-(4-(trifluoromethyl)phenyl)allyl)-1H-benzo[d]imidazole (1181811-67-5)

Guidance literature:

With potassium carbonate; In tetrahydrofuran; at 135 ℃; for 24h; Inert atmosphere;

DOI:10.1039/b902878a

Reference yield:

1-(2-(4-(trifluoromethyl)phenyl)allyl)-1H-benzo[d]imidazole (1181811-67-5) → 2-(4-trifluoromethylphenyl)-2,3-dihydro-1H-benzo[d]pyrrolo[1,2-a]imidazole + 2-(4-trifluoromethylphenyl)-2,3-dihydro-1H-benzo[d]pyrrolo[1,2-a]imidazole

Guidance literature:

With chlorobis(cyclooctene)rhodium(I) dimer; (1S,1S',2R,2R')-1,1'-di-tert-butyl-(2,2’)-diphospholane; In tetrahydrofuran; at 175 ℃; for 24h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;

DOI:10.1039/b902878a

upstream raw materials:

2-(1H-benzo[d]imidazol-1-yl)-1-(4-(trifluoromethyl)henyl)ethanone

Methyltriphenylphosphonium bromide