Nα-(4-(N-Cbz)aminomethylbenzoyl)-L-ornithine 1-naphthalenemethylamide

Base Information

• Chemical Name: Nα-(4-(N-Cbz)aminomethylbenzoyl)-L-ornithine 1-naphthalenemethylamide
• CAS No.: 370594-21-1
• Molecular Formula: C₃₂H₃₄N₄O₄
• Molecular Weight: 538.646
• Mol file: 370594-21-1.mol

Synonyms:Nα-(4-(N-Cbz)aminomethylbenzoyl)-L-ornithine 1-naphthalenemethylamide

Chemical Property of Nα-(4-(N-Cbz)aminomethylbenzoyl)-L-ornithine 1-naphthalenemethylamide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of Nα-(4-(N-Cbz)aminomethylbenzoyl)-L-ornithine 1-naphthalenemethylamide

There total 1 articles about Nα-(4-(N-Cbz)aminomethylbenzoyl)-L-ornithine 1-naphthalenemethylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Nδ-Boc-L-ornithine 1-naphthalenemethylamide (370594-66-4) + 4-((benzyloxycarbonylamino)methyl)benzoic acid (58933-52-1) → Nα-(4-(N-Cbz)aminomethylbenzoyl)-L-ornithine 1-naphthalenemethylamide (370594-21-1)

Guidance literature:

Nδ-Boc-L-ornithine 1-naphthalenemethylamide; 4-((benzyloxycarbonylamino)methyl)benzoic acid; With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 ℃; for 24h;

With hydrogenchloride; In 1,4-dioxane; methanol; at 20 ℃; for 1.16667h;

Reference yield:

pyridine-2-carbaldehyde (1121-60-4) + Nα-(4-(N-Cbz)aminomethylbenzoyl)-L-ornithine 1-naphthalenemethylamide (370594-21-1) → (S)-2-((4-(N-Cbz)aminomethylbenzoyl)amino)-5-(2-picolylamino)valerate 1-naphthalenemethylamide (369655-54-9)

Guidance literature:

With sodium cyanoborohydride; acetic acid; triethylamine; In methanol; at 20 ℃; for 48h; pH=5;

upstream raw materials:

Nδ-Boc-L-ornithine 1-naphthalenemethylamide

4-((benzyloxycarbonylamino)methyl)benzoic acid

Downstream raw materials:

(S)-2-((4-(N-Cbz)aminomethylbenzoyl)amino)-5-(2-picolylamino)valerate 1-naphthalenemethylamide