thiophenoxy-2 naphthalene carbonitrile-1

Base Information

• Chemical Name: thiophenoxy-2 naphthalene carbonitrile-1
• CAS No.: 103408-14-6
• Molecular Formula: C₁₇H₁₁NS
• Molecular Weight: 261.347
• Mol file: 103408-14-6.mol

Synonyms:thiophenoxy-2 naphthalene carbonitrile-1

Chemical Property of thiophenoxy-2 naphthalene carbonitrile-1

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of thiophenoxy-2 naphthalene carbonitrile-1

There total 2 articles about thiophenoxy-2 naphthalene carbonitrile-1 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

phenyl thiocyanate (5285-87-0) + 2-(trimethylsilyl)naphth-1-yl triflate → thiophenoxy-2 naphthalene carbonitrile-1 (103408-14-6)

Guidance literature:

With oxygen; palladium diacetate; cesium fluoride; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In acetonitrile; at 40 ℃; for 24h;

DOI:10.1021/acs.orglett.5b00494

Reference yield:

diphenyldisulfane (882-33-7) + 1-Cyanonaphthalene (86-53-3) → thiophenoxy-2 naphthalene carbonitrile-1 (103408-14-6)

Guidance literature:

With tetramethylpiperidine amide; methyllithium; Yield given. Multistep reaction; 1.) THF, diethyl ether, -78 deg C, 35 min; 2.) THF, diethyl ether, -78 deg C, 2 h, warming to r.t., 1 h;

upstream raw materials:

diphenyldisulfane

1-Cyanonaphthalene

phenyl thiocyanate