1-(4-Trifluoromethyl-benzenesulfonyl)-piperazine hydrochloride

Base Information

Chemical Name:1-(4-Trifluoromethyl-benzenesulfonyl)-piperazine hydrochloride
CAS No.:793679-07-9
Molecular Formula:C11H13 F3 N2 O2 S
Molecular Weight:294.298
Hs Code.:
European Community (EC) Number:823-138-0
DSSTox Substance ID:DTXSID40697993
Mol file:793679-07-9.mol

Synonyms:793679-07-9;1-(4-TRIFLUOROMETHYL-BENZENESULFONYL)-PIPERAZINE HYDROCHLORIDE;1-[4-(trifluoromethyl)phenyl]sulfonylpiperazine;hydrochloride;1044761-09-2;SCHEMBL3249218;DTXSID40697993;AKOS025980285;AT27764;1-(4-trifluoromethylphenylsulfonyl)piperazine HCl;EN300-24709438;1-(4-trifluoromethylphenylsulfonyl)piperazine hydrochloride;1-((4-(TRIFLUOROMETHYL)PHENYL)SULFONYL)PIPERAZINE HCL;1-((4-(Trifluoromethyl)phenyl)sulfonyl)piperazine hydrochloride;1-((4-(Trifluoromethyl)phenyl)sulfonyl)piperazinehydrochloride;1-[4-(TRIFLUOROMETHYL)BENZENESULFONYL]PIPERAZINE HYDROCHLORIDE;1-[4-(Trifluoromethyl)benzene-1-sulfonyl]piperazine--hydrogen chloride (1/1)

Suppliers and Price of 1-(4-Trifluoromethyl-benzenesulfonyl)-piperazine hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-([4-(TRIFLUOROMETHYL)PHENYL]SULFONYL)PIPERAZINE 95.00%
5G
$ 1168.42

American Custom Chemicals Corporation
1-([4-(TRIFLUOROMETHYL)PHENYL]SULFONYL)PIPERAZINE 95.00%
2.5G
$ 983.88

American Custom Chemicals Corporation
1-([4-(TRIFLUOROMETHYL)PHENYL]SULFONYL)PIPERAZINE 95.00%
1G
$ 721.57

AK Scientific
1-(4-Trifluoromethyl-benzenesulfonyl)-piperazinehydrochloride
250mg
$ 264.00

AK Scientific
1-(4-Trifluoromethyl-benzenesulfonyl)-piperazinehydrochloride
100mg
$ 224.00

A1 Biochem Labs
1-[4-(Trifluoromethyl)benzenesulfonyl]piperazine 95%
5 g
$ 620.00

Total 3 raw suppliers

Chemical Property of 1-(4-Trifluoromethyl-benzenesulfonyl)-piperazine hydrochloride

Chemical Property:

PSA：57.79000
LogP:3.44880
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:2
Exact Mass:330.0416610
Heavy Atom Count:20
Complexity:391

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

1-([4-(TRIFLUOROMETHYL)PHENYL]SULFONYL)PIPERAZINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1)S(=O)(=O)C2=CC=C(C=C2)C(F)(F)F.Cl

Technology Process of 1-(4-Trifluoromethyl-benzenesulfonyl)-piperazine hydrochloride

There total 4 articles about 1-(4-Trifluoromethyl-benzenesulfonyl)-piperazine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 31.0%

: 2991-42-6
4-trifluorophenylsulfonyl chloride

: 57260-71-6
1-t-Butoxycarbonylpiperazine

: 793679-07-9
1-{[4-(trifluoromethyl)phenyl]sulfonyl}piperazine

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃;

Reference yield:

: 110-85-0
piperazine

: 2991-42-6
4-trifluorophenylsulfonyl chloride

: 793679-07-9
1-{[4-(trifluoromethyl)phenyl]sulfonyl}piperazine

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 ℃; for 1h;
DOI:10.1016/j.ejmech.2018.09.068

Reference yield:

: 1204535-09-0
1,1-dimethylethyl 4-{[4-(trifluoromethyl)phenyl]sulfonyl}-1-piperazinecarboxylate

: 793679-07-9
1-{[4-(trifluoromethyl)phenyl]sulfonyl}piperazine

Guidance literature:: 1,1-dimethylethyl 4-{[4-(trifluoromethyl)phenyl]sulfonyl}-1-piperazinecarboxylate; With hydrogenchloride; water; In 1,4-dioxane;

With sodium hydroxide; In dichloromethane; water;