1,1-dimethylethyl 4-[5-({5-methyl-4-[(2-{[(1-methylethyl)amino]carbonyl}phenyl)amino]-2-pyrimidinyl}amino)-2-pyridinyl]-1-piperidinecarboxylate

Base Information

Chemical Name:1,1-dimethylethyl 4-[5-({5-methyl-4-[(2-{[(1-methylethyl)amino]carbonyl}phenyl)amino]-2-pyrimidinyl}amino)-2-pyridinyl]-1-piperidinecarboxylate
CAS No.:1089654-02-3
Molecular Formula:C₃₀H₃₉N₇O₃
Molecular Weight:545.685
Hs Code.:

Synonyms:1,1-dimethylethyl 4-[5-({5-methyl-4-[(2-{[(1-methylethyl)amino]carbonyl}phenyl)amino]-2-pyrimidinyl}amino)-2-pyridinyl]-1-piperidinecarboxylate

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Chemical Property of 1,1-dimethylethyl 4-[5-({5-methyl-4-[(2-{[(1-methylethyl)amino]carbonyl}phenyl)amino]-2-pyrimidinyl}amino)-2-pyridinyl]-1-piperidinecarboxylate

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Technology Process of 1,1-dimethylethyl 4-[5-({5-methyl-4-[(2-{[(1-methylethyl)amino]carbonyl}phenyl)amino]-2-pyrimidinyl}amino)-2-pyridinyl]-1-piperidinecarboxylate

There total 1 articles about 1,1-dimethylethyl 4-[5-({5-methyl-4-[(2-{[(1-methylethyl)amino]carbonyl}phenyl)amino]-2-pyrimidinyl}amino)-2-pyridinyl]-1-piperidinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 31.0%

: 885693-48-1
5-amino-3',4',5',6'-tetrahydro-2'H-(2,4'-bipyridinyl)-1'-carboxylic acid tert-butyl ester

: 1089653-88-2
2-[(2-bromo-5-methyl-4-pyrimidinyl)amino]-N-(1-methylethyl)benzamide

: 1089654-02-3
1,1-dimethylethyl 4-[5-({5-methyl-4-[(2-{[(1-methylethyl)amino]carbonyl}phenyl)amino]-2-pyrimidinyl}amino)-2-pyridinyl]-1-piperidinecarboxylate

Guidance literature:: With caesium carbonate; palladium diacetate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In 1,4-dioxane; at 50 - 80 ℃; for 25.25h;

Reference yield:

: 1089654-02-3
1,1-dimethylethyl 4-[5-({5-methyl-4-[(2-{[(1-methylethyl)amino]carbonyl}phenyl)amino]-2-pyrimidinyl}amino)-2-pyridinyl]-1-piperidinecarboxylate

: C₂₅H₃₁N₇O

Guidance literature:: 1,1-dimethylethyl 4-[5-({5-methyl-4-[(2-{[(1-methylethyl)amino]carbonyl}phenyl)amino]-2-pyrimidinyl}amino)-2-pyridinyl]-1-piperidinecarboxylate; With hydrogenchloride; water; at 20 ℃; for 1.5h;

With water; sodium hydrogencarbonate;