2-(4-Chlorophenyl)-1-(2-hydroxy-4-methoxyphenyl)ethanone

Base Information

Chemical Name:2-(4-Chlorophenyl)-1-(2-hydroxy-4-methoxyphenyl)ethanone
CAS No.:79744-48-2
Molecular Formula:C15H13 Cl O3
Molecular Weight:276.719
Hs Code.:
European Community (EC) Number:650-987-2
DSSTox Substance ID:DTXSID50399512
Mol file:79744-48-2.mol

Synonyms:2-(4-chlorophenyl)-1-(2-hydroxy-4-methoxyphenyl)ethanone;79744-48-2;Ethanone,2-(4-chlorophenyl)-1-(2-hydroxy-4-methoxyphenyl)-;DTXSID50399512;MFCD03934793;AKOS024408710

Suppliers and Price of 2-(4-Chlorophenyl)-1-(2-hydroxy-4-methoxyphenyl)ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-(4-CHLOROPHENYL)-1-(2-HYDROXY-4-METHOXYPHENYL)ETHANONE 95.00%
10G
$ 7882.88

American Custom Chemicals Corporation
2-(4-CHLOROPHENYL)-1-(2-HYDROXY-4-METHOXYPHENYL)ETHANONE 95.00%
5G
$ 4244.63

American Custom Chemicals Corporation
2-(4-CHLOROPHENYL)-1-(2-HYDROXY-4-METHOXYPHENYL)ETHANONE 95.00%
1G
$ 1030.84

Total 4 raw suppliers

Chemical Property of 2-(4-Chlorophenyl)-1-(2-hydroxy-4-methoxyphenyl)ethanone

Chemical Property:

PSA：46.53000
LogP:3.47960
XLogP3:4.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:276.0553220
Heavy Atom Count:19
Complexity:300

Purity/Quality:

97% ^*data from raw suppliers

2-(4-CHLOROPHENYL)-1-(2-HYDROXY-4-METHOXYPHENYL)ETHANONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=C(C=C1)C(=O)CC2=CC=C(C=C2)Cl)O

Technology Process of 2-(4-Chlorophenyl)-1-(2-hydroxy-4-methoxyphenyl)ethanone

There total 3 articles about 2-(4-Chlorophenyl)-1-(2-hydroxy-4-methoxyphenyl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 15485-64-0
2-(4-chlorophenyl)-1-(2,4-dihydroxyphenyl)ethan-1-one

: 77-78-1
dimethyl sulfate

: 79744-48-2
2-(4-chlorophenyl)-1-(2-hydroxy-4-methoxyphenyl)ethan-1-one

Guidance literature:: With potassium carbonate; In acetone; for 2h; Reflux;
DOI:10.1007/s10593-015-1777-3

Reference yield:

: 140-53-4
p-chlorobenzyl cyanide

: 79744-48-2
2-(4-chlorophenyl)-1-(2-hydroxy-4-methoxyphenyl)ethan-1-one

Guidance literature:: Multi-step reaction with 3 steps

1: zinc(II) chloride; hydrogenchloride / diethyl ether; water / 0 °C

2: water / Reflux

3: potassium carbonate / acetone / 2 h / Reflux

With hydrogenchloride; water; potassium carbonate; zinc(II) chloride; In diethyl ether; water; acetone;
DOI:10.1007/s10895-016-1930-0

Reference yield:

: 108-46-3
recorcinol

: 79744-48-2
2-(4-chlorophenyl)-1-(2-hydroxy-4-methoxyphenyl)ethan-1-one

Guidance literature:: Multi-step reaction with 3 steps

1: zinc(II) chloride; hydrogenchloride / diethyl ether; water / 0 °C

2: water / Reflux

3: potassium carbonate / acetone / 2 h / Reflux

With hydrogenchloride; water; potassium carbonate; zinc(II) chloride; In diethyl ether; water; acetone;
DOI:10.1007/s10895-016-1930-0