1-(2-Fluorophenyl)-2-oxopyrrolidine-3-carboxylic acid

Base Information

Chemical Name:1-(2-Fluorophenyl)-2-oxopyrrolidine-3-carboxylic acid
CAS No.:618070-32-9
Molecular Formula:C₁₁H₁₀FNO₃
Molecular Weight:223.204
Hs Code.:
European Community (EC) Number:632-176-5
DSSTox Substance ID:DTXSID601212529
Mol file:618070-32-9.mol

Synonyms:1-(2-fluorophenyl)-2-oxopyrrolidine-3-carboxylic acid;618070-32-9;1-(2-FLUOROPHENYL)-2-OXO-3-PYRROLIDINECARBOXYLIC ACID;SCHEMBL892631;WUHKWNJTHHFDNQ-UHFFFAOYSA-N;DTXSID601212529;AKOS000164212;AKOS022203212

Suppliers and Price of 1-(2-Fluorophenyl)-2-oxopyrrolidine-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Heterocyclics
1-(2-Fluorophenyl)-2-oxopyrrolidine-3-carboxylic acid 97%
5g
$ 750.00

Heterocyclics
1-(2-Fluorophenyl)-2-oxopyrrolidine-3-carboxylic acid 97%
1g
$ 250.00

American Custom Chemicals Corporation
1-(2-FLUOROPHENYL)-2-OXOPYRROLIDINE-3-CARBOXYLIC ACID 95.00%
10G
$ 7882.88

American Custom Chemicals Corporation
1-(2-FLUOROPHENYL)-2-OXOPYRROLIDINE-3-CARBOXYLIC ACID 95.00%
5G
$ 4244.63

American Custom Chemicals Corporation
1-(2-FLUOROPHENYL)-2-OXOPYRROLIDINE-3-CARBOXYLIC ACID 95.00%
1G
$ 1030.84

Total 3 raw suppliers

Chemical Property of 1-(2-Fluorophenyl)-2-oxopyrrolidine-3-carboxylic acid

Chemical Property:

XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:223.06447134
Heavy Atom Count:16
Complexity:308

Purity/Quality:

99% ^*data from raw suppliers

1-(2-Fluorophenyl)-2-oxopyrrolidine-3-carboxylic acid 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CN(C(=O)C1C(=O)O)C2=CC=CC=C2F

Technology Process of 1-(2-Fluorophenyl)-2-oxopyrrolidine-3-carboxylic acid

There total 1 articles about 1-(2-Fluorophenyl)-2-oxopyrrolidine-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.4%

: 5617-70-9
cycl-isopropylidene cyclopropane-1,1-dicarboxylate

: 348-54-9
2-Fluoroaniline

: 618070-32-9
1-(2-fluorophenyl)-2-oxopyrrolidine-3-carboxylicacid

Guidance literature:: In N,N-dimethyl-formamide; at 30 - 35 ℃; for 12h;
DOI:10.1016/j.bioorg.2020.103970

Reference yield: 56.2%

: 618070-32-9
1-(2-fluorophenyl)-2-oxopyrrolidine-3-carboxylicacid

: 74-88-4
methyl iodide

: 1-(2-fluorophenyl)-3-methyl-2-oxopyrrolidine-3-carboxylic acid

Guidance literature:: 1-(2-fluorophenyl)-2-oxopyrrolidine-3-carboxylicacid; With sodium hydride; In tetrahydrofuran; at -5 ℃; for 0.5h;

methyl iodide; In tetrahydrofuran;
DOI:10.1016/j.bioorg.2020.103970

Reference yield: 44.0%

: 55747-73-4
5-chlorotryptamine hydrochloride

: 618070-32-9
1-(2-fluorophenyl)-2-oxopyrrolidine-3-carboxylicacid

: 1258502-38-3
N-(2-(5-chloro-1H-indol-3-yl)ethyl)-1-(2-fluorophenyl)-2-oxopyrrolidine-3-carboxamide

Guidance literature:: With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide;