3-[3,5-dimethyl-4-(4-[⁽¹¹⁾C]methylpiperazine-1-carbonyl)-1H-pyrrol-2-ylmethylene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid (3-chlorophenyl)methylamide hydrochloride

Base Information

• Chemical Name: 3-[3,5-dimethyl-4-(4-[⁽¹¹⁾C]methylpiperazine-1-carbonyl)-1H-pyrrol-2-ylmethylene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid (3-chlorophenyl)methylamide hydrochloride
• CAS No.: 1202854-09-8
• Molecular Formula: C₂₈H₃₀ClN₅O₄S
• Molecular Weight: 567.085

Synonyms:3-[3,5-dimethyl-4-(4-[⁽¹¹⁾C]methylpiperazine-1-carbonyl)-1H-pyrrol-2-ylmethylene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid (3-chlorophenyl)methylamide hydrochloride

Chemical Property of 3-[3,5-dimethyl-4-(4-[⁽¹¹⁾C]methylpiperazine-1-carbonyl)-1H-pyrrol-2-ylmethylene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid (3-chlorophenyl)methylamide hydrochloride

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Technology Process of 3-[3,5-dimethyl-4-(4-[⁽¹¹⁾C]methylpiperazine-1-carbonyl)-1H-pyrrol-2-ylmethylene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid (3-chlorophenyl)methylamide hydrochloride

There total 1 articles about 3-[3,5-dimethyl-4-(4-[⁽¹¹⁾C]methylpiperazine-1-carbonyl)-1H-pyrrol-2-ylmethylene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid (3-chlorophenyl)methylamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

[11C]methyl iodide (54245-42-0) + 3-[3,5-dimethyl-4-(piperazine-1-carbonyl)-1H-pyrrol-2-ylmethylene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid (3-chlorophenyl)methylamide hydrochloride (1202780-14-0) → 3-[3,5-dimethyl-4-(4-[(11)C]methylpiperazine-1-carbonyl)-1H-pyrrol-2-ylmethylene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid (3-chlorophenyl)methylamide hydrochloride (1202854-09-8)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 140 ℃; for 0.166667h;

DOI:10.1021/jm900803q

upstream raw materials:

[11C]methyl iodide

3-[3,5-dimethyl-4-(piperazine-1-carbonyl)-1H-pyrrol-2-ylmethylene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid (3-chlorophenyl)methylamide hydrochloride

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