2-acetamido-9-(2-acetoxyethoxymethyl)-8-benzylthio-6-oxopurine

Base Information

• Chemical Name: 2-acetamido-9-(2-acetoxyethoxymethyl)-8-benzylthio-6-oxopurine
• CAS No.: 661476-44-4
• Molecular Formula: C₁₉H₂₁N₅O₅S
• Molecular Weight: 431.472
• Mol file: 661476-44-4.mol

Synonyms:2-acetamido-9-(2-acetoxyethoxymethyl)-8-benzylthio-6-oxopurine

Chemical Property of 2-acetamido-9-(2-acetoxyethoxymethyl)-8-benzylthio-6-oxopurine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 2-acetamido-9-(2-acetoxyethoxymethyl)-8-benzylthio-6-oxopurine

There total 1 articles about 2-acetamido-9-(2-acetoxyethoxymethyl)-8-benzylthio-6-oxopurine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

benzyl bromide (100-39-0) + 8-thio-9-((2-acetoxyethoxy)methyl)-N2-acetylguanine → 2-acetamido-9-(2-acetoxyethoxymethyl)-8-benzylthio-6-oxopurine (661476-44-4)

Guidance literature:

With sodium hydroxide; at 20 ℃; for 36h;

DOI:10.1023/A:1023732827820

Reference yield: 84.0%

diphenylcarbamic chloride (83-01-2) + 2-acetamido-9-(2-acetoxyethoxymethyl)-8-benzylthio-6-oxopurine (661476-44-4) → 9-[(2-acetoxyethoxy)methyl]-2-(acetylamino)-8-(benzylsulfanyl)-6-(diphenylcarbamoyloxy)-9H-purine (1092359-59-5)

Guidance literature:

With pyridine; N-ethyl-N,N-diisopropylamine; at 20 ℃; for 4h;

DOI:10.1055/s-2008-1067254

upstream raw materials:

benzyl bromide

Downstream raw materials:

9-[(2-acetoxyethoxy)methyl]-2-(acetylamino)-8-(benzylsulfanyl)-6-(diphenylcarbamoyloxy)-9H-purine