3-oxo-4-(3-trifluoromethyl-phenyl)-butyric acid ethyl ester

Base Information

Chemical Name:3-oxo-4-(3-trifluoromethyl-phenyl)-butyric acid ethyl ester
CAS No.:894802-88-1
Molecular Formula:C₁₃H₁₃F₃O₃
Molecular Weight:274.24
Hs Code.:
Mol file:894802-88-1.mol

Synonyms:3-oxo-4-(3-trifluoromethyl-phenyl)-butyric acid ethyl ester

Suppliers and Price of 3-oxo-4-(3-trifluoromethyl-phenyl)-butyric acid ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
ethyl4-(3-(trifluoromethyl)phenyl)-3-oxobutanoate 95
5g
$ 1467.00

American Custom Chemicals Corporation
ETHYL 4-(3-(TRIFLUOROMETHYL)PHENYL)-3-OXOBUTANOATE 95.00%
5MG
$ 498.59

Acrotein
Ethyl3-oxo-4-(3-trifluoromethylphenyl)butanoate 97%
0.5g
$ 146.67

Total 7 raw suppliers

Chemical Property of 3-oxo-4-(3-trifluoromethyl-phenyl)-butyric acid ethyl ester

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

ethyl4-(3-(trifluoromethyl)phenyl)-3-oxobutanoate 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-oxo-4-(3-trifluoromethyl-phenyl)-butyric acid ethyl ester

There total 2 articles about 3-oxo-4-(3-trifluoromethyl-phenyl)-butyric acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 2033-24-1
cycl-isopropylidene malonate

: 64-17-5
ethanol

: 2003-14-7
(3-trifluoromethyl-phenyl)-acetyl chloride

: 894802-88-1
3-oxo-4-(3-trifluoromethyl-phenyl)-butyric acid ethyl ester

Guidance literature:: cycl-isopropylidene malonate; (3-trifluoromethyl-phenyl)-acetyl chloride; With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 - 20 ℃; for 4h;

ethanol; for 2h; Heating;
DOI:10.1021/ja060729t

Reference yield:

: 351-35-9
3-(trifluoromethyl)phenylacetic acid

: 894802-88-1
3-oxo-4-(3-trifluoromethyl-phenyl)-butyric acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: SOCl₂ / CH₂Cl₂ / Heating

2.1: DIEA / CH₂Cl₂ / 4 h / 0 - 20 °C

2.2: 96 percent / 2 h / Heating

With thionyl chloride; N-ethyl-N,N-diisopropylamine; In dichloromethane;
DOI:10.1021/ja060729t