2-(4-Chlorophenoxy)-1-(2-sulfanylidene-1,3-thiazolidin-3-yl)ethan-1-one

Base Information

• Chemical Name: 2-(4-Chlorophenoxy)-1-(2-sulfanylidene-1,3-thiazolidin-3-yl)ethan-1-one
• CAS No.: 123529-83-9
• Molecular Formula: C₁₁H₁₀ClNO₂S₂
• Molecular Weight: 287.791
• DSSTox Substance ID: DTXSID501201872
• Mol file: 123529-83-9.mol

Synonyms:123529-83-9;2-(4-chlorophenoxy)-1-(2-sulfanylidene-1,3-thiazolidin-3-yl)ethan-1-one;2-(4-chlorophenoxy)-1-(2-sulfanylidene-1,3-thiazolidin-3-yl)ethanone;DTXSID501201872;STL466228;AKOS021965778;NS-04794;CS-0268413;EN300-302686;2-(4-Chlorophenoxy)-1-(2-thioxo-3-thiazolidinyl)ethanone;2-(4-Chlorophenoxy)-1-(2-thioxothiazolidin-3-yl)ethan-1-one;2-(4-chlorophenoxy)-1-(2-thioxo-1,3-thiazolidin-3-yl)ethanone

Chemical Property of 2-(4-Chlorophenoxy)-1-(2-sulfanylidene-1,3-thiazolidin-3-yl)ethan-1-one

Chemical Property:

• XLogP3: 3.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 286.9841486
• Heavy Atom Count: 17
• Complexity: 306

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1CSC(=S)N1C(=O)COC2=CC=C(C=C2)Cl

Technology Process of 2-(4-Chlorophenoxy)-1-(2-sulfanylidene-1,3-thiazolidin-3-yl)ethan-1-one

There total 1 articles about 2-(4-Chlorophenoxy)-1-(2-sulfanylidene-1,3-thiazolidin-3-yl)ethan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

thiazolidine-2-thione (134469-06-0) + 4-chlorophenyloxyacetyl chloride (4122-68-3) → 3-(4-chlorophenoxyacetyl)-thiazolidine-2-thione (123529-83-9)

Guidance literature:

With triethylamine; In dichloromethane;

DOI:10.1016/S0040-4020(01)80906-6

Reference yield:

alpha-D-glucopyranose (492-62-6) + 3-(4-chlorophenoxyacetyl)-thiazolidine-2-thione (123529-83-9) → (4-Chloro-phenoxy)-acetic acid (2R,3S,4S,5R,6S)-3,4,5,6-tetrahydroxy-tetrahydro-pyran-2-ylmethyl ester (135363-43-8) + (4-Chloro-phenoxy)-acetic acid (2R,3S,4S,5R,6R)-3,4,5,6-tetrahydroxy-tetrahydro-pyran-2-ylmethyl ester (135363-54-1)

Guidance literature:

With triethylamine; In N,N-dimethyl-formamide; for 2h; Title compound not separated from byproducts; Ambient temperature;

DOI:10.1016/S0040-4020(01)80906-6

upstream raw materials:

thiazolidine-2-thione

4-chlorophenyloxyacetyl chloride

Downstream raw materials:

(4-Chloro-phenoxy)-acetic acid (2R,3S,4S,5R,6S)-3,4,5,6-tetrahydroxy-tetrahydro-pyran-2-ylmethyl ester

(4-Chloro-phenoxy)-acetic acid (2R,3S,4S,5R,6R)-3,4,5,6-tetrahydroxy-tetrahydro-pyran-2-ylmethyl ester