C₂₁H₁₉NO₃

Base Information

• Chemical Name: C₂₁H₁₉NO₃
• CAS No.: 1027369-26-1
• Molecular Formula: C₂₁H₁₉NO₃
• Molecular Weight: 333.387
• Mol file: 1027369-26-1.mol

Synonyms:C₂₁H₁₉NO₃

Chemical Property of C₂₁H₁₉NO₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₁H₁₉NO₃

There total 7 articles about C₂₁H₁₉NO₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C28H25NO3 (934292-61-2) → C21H19NO3 (1027369-26-1)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethyl acetate; for 14h; under 760.051 Torr;

DOI:10.1021/jo062083t

Reference yield:

C25H26O4 (934292-39-4) → C21H19NO3 (1027369-26-1)

Guidance literature:

Multi-step reaction with 4 steps

1: trifluoroacetic acid

2: oxalyl chloride / dimethylformamide; CH₂Cl₂ / 5 h / 20 °C

3: triethylamine / CH₂Cl₂ / 14 h / 20 °C

4: hydrogen / palladium on carbon / ethyl acetate / 14 h / 760.05 Torr

With oxalyl dichloride; hydrogen; triethylamine; trifluoroacetic acid; palladium on activated charcoal; In dichloromethane; ethyl acetate; N,N-dimethyl-formamide;

DOI:10.1021/jo062083t

Reference yield:

C21H18O4 (934292-45-2) → C21H19NO3 (1027369-26-1)

Guidance literature:

Multi-step reaction with 3 steps

1: oxalyl chloride / dimethylformamide; CH₂Cl₂ / 5 h / 20 °C

2: triethylamine / CH₂Cl₂ / 14 h / 20 °C

3: hydrogen / palladium on carbon / ethyl acetate / 14 h / 760.05 Torr

With oxalyl dichloride; hydrogen; triethylamine; palladium on activated charcoal; In dichloromethane; ethyl acetate; N,N-dimethyl-formamide;

DOI:10.1021/jo062083t

upstream raw materials:

C₂₈H₂₅NO₃

C₂₅H₂₆O₄

C₂₁H₁₈O₄

tert-butyl 5-(benzyloxy)-2-iodobenzoate