(1S,2R,3S)-1-acetoxymethyl-2-(2-(benzyloxy)ethyl)-3-(3-((tert-butyldimethylsilyl)oxy)propyl)-2-hydroxy-3-(hydroxymethyl)cyclopentane

Base Information

Chemical Name:(1S,2R,3S)-1-acetoxymethyl-2-(2-(benzyloxy)ethyl)-3-(3-((tert-butyldimethylsilyl)oxy)propyl)-2-hydroxy-3-(hydroxymethyl)cyclopentane
CAS No.:1246189-60-5
Molecular Formula:C₂₇H₄₆O₆Si
Molecular Weight:494.744
Hs Code.:

Synonyms:(1S,2R,3S)-1-acetoxymethyl-2-(2-(benzyloxy)ethyl)-3-(3-((tert-butyldimethylsilyl)oxy)propyl)-2-hydroxy-3-(hydroxymethyl)cyclopentane

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (1S,2R,3S)-1-acetoxymethyl-2-(2-(benzyloxy)ethyl)-3-(3-((tert-butyldimethylsilyl)oxy)propyl)-2-hydroxy-3-(hydroxymethyl)cyclopentane

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Technology Process of (1S,2R,3S)-1-acetoxymethyl-2-(2-(benzyloxy)ethyl)-3-(3-((tert-butyldimethylsilyl)oxy)propyl)-2-hydroxy-3-(hydroxymethyl)cyclopentane

There total 1 articles about (1S,2R,3S)-1-acetoxymethyl-2-(2-(benzyloxy)ethyl)-3-(3-((tert-butyldimethylsilyl)oxy)propyl)-2-hydroxy-3-(hydroxymethyl)cyclopentane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 1246189-50-3
(1S,2R,3S)-1-acetoxymethyl-2-(2-(benzyloxy)ethyl)-2-hydroxy-3-(hydroxymethyl)-3-(3-hydroxypropyl)cyclopentane

: 18162-48-6
tert-butyldimethylsilyl chloride

: 1246189-60-5
(1S,2R,3S)-1-acetoxymethyl-2-(2-(benzyloxy)ethyl)-3-(3-((tert-butyldimethylsilyl)oxy)propyl)-2-hydroxy-3-(hydroxymethyl)cyclopentane

Guidance literature:: With 1H-imidazole; In dichloromethane; at 20 ℃; for 6.5h; Inert atmosphere;
DOI:10.1016/j.tetasy.2010.03.047

Reference yield: 90.0%

: 1246189-60-5
(1S,2R,3S)-1-acetoxymethyl-2-(2-(benzyloxy)ethyl)-3-(3-((tert-butyldimethylsilyl)oxy)propyl)-2-hydroxy-3-(hydroxymethyl)cyclopentane

: 1005-56-7
phenylcarbonochloridothioate

: 1246189-79-6
C₃₄H₅₀O₇SSi

Guidance literature:: (1S,2R,3S)-1-acetoxymethyl-2-(2-(benzyloxy)ethyl)-3-(3-((tert-butyldimethylsilyl)oxy)propyl)-2-hydroxy-3-(hydroxymethyl)cyclopentane; With pyridine; dmap; In dichloromethane; at 20 ℃; for 0.0333333h; Inert atmosphere;

phenylcarbonochloridothioate; In dichloromethane; Inert atmosphere;
DOI:10.1016/j.tetasy.2010.03.047