δ--S-(acetamidomethyl)-L-cysteinyl-o-methyl-D-allothreonine methyl ester

Base Information

• Chemical Name: δ--S-(acetamidomethyl)-L-cysteinyl-o-methyl-D-allothreonine methyl ester
• CAS No.: 115288-60-3
• Molecular Formula: C₂₆H₃₈N₄O₁₀S
• Molecular Weight: 598.675
• Mol file: 115288-60-3.mol

Synonyms:δ--S-(acetamidomethyl)-L-cysteinyl-o-methyl-D-allothreonine methyl ester

Chemical Property of δ--S-(acetamidomethyl)-L-cysteinyl-o-methyl-D-allothreonine methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of δ--S-(acetamidomethyl)-L-cysteinyl-o-methyl-D-allothreonine methyl ester

There total 2 articles about δ--S-(acetamidomethyl)-L-cysteinyl-o-methyl-D-allothreonine methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

Cys(SAcm)-D-alloThr(OMe)OMe (115270-21-8) + Z-Adp(OMe)OH (115304-82-0) → δ--S-(acetamidomethyl)-L-cysteinyl-o-methyl-D-allothreonine methyl ester (115288-60-3)

Guidance literature:

With mercaptoethyl alcohol; sodium phosphate; papain; In water; N,N-dimethyl-formamide; for 15h; Ambient temperature;

DOI:10.1021/ja00223a042

Reference yield:

(S)-dimethyl 2-(benzyloxycarbonylamino)hexanedioate (15366-20-8) → δ--S-(acetamidomethyl)-L-cysteinyl-o-methyl-D-allothreonine methyl ester (115288-60-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 92 percent / 0.05 M potassium phosphate, 0.05 N NaOH / porcine panceatic lipase / H₂O

2: 46 percent / 0.1 M sodium phosphate, 2 M mercaptoethanol / papain / dimethylformamide; H₂O / 15 h / Ambient temperature

With sodium hydroxide; potassium phosphate; mercaptoethyl alcohol; sodium phosphate; porcine panceatic lipase; papain; In water; N,N-dimethyl-formamide;

DOI:10.1021/ja00223a042

upstream raw materials:

Cys(SAcm)-D-alloThr(OMe)OMe

Z-Adp(OMe)OH

(S)-dimethyl 2-(benzyloxycarbonylamino)hexanedioate