{5-[5-(3-Chloro-phenyl)-furan-2-yl]-tetrazol-2-yl}-acetic acid ethyl ester

Base Information

• Chemical Name: {5-[5-(3-Chloro-phenyl)-furan-2-yl]-tetrazol-2-yl}-acetic acid ethyl ester
• CAS No.: 93674-59-0
• Molecular Formula: C₁₅H₁₃ClN₄O₃
• Molecular Weight: 332.746
• Mol file: 93674-59-0.mol

Synonyms:{5-[5-(3-Chloro-phenyl)-furan-2-yl]-tetrazol-2-yl}-acetic acid ethyl ester

Chemical Property of {5-[5-(3-Chloro-phenyl)-furan-2-yl]-tetrazol-2-yl}-acetic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of {5-[5-(3-Chloro-phenyl)-furan-2-yl]-tetrazol-2-yl}-acetic acid ethyl ester

There total 1 articles about {5-[5-(3-Chloro-phenyl)-furan-2-yl]-tetrazol-2-yl}-acetic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

ethyl bromoacetate (105-36-2) + 5-[5-(3-chloro-phenyl)-furan-2-yl]-1(2)H-tetrazole (74637-99-3) → {5-[5-(3-Chloro-phenyl)-furan-2-yl]-tetrazol-2-yl}-acetic acid ethyl ester (93674-59-0) + {5-[5-(3-Chloro-phenyl)-furan-2-yl]-tetrazol-1-yl}-acetic acid ethyl ester (92973-06-3)

Guidance literature:

With sodium ethanolate; In ethanol; for 16h; Heating;

DOI:10.1135/cccc19841699

Reference yield: 96.0%

{5-[5-(3-Chloro-phenyl)-furan-2-yl]-tetrazol-2-yl}-acetic acid ethyl ester (93674-59-0) → {5-[5-(3-Chloro-phenyl)-furan-2-yl]-tetrazol-2-yl}-acetic acid (93789-15-2)

Guidance literature:

With hydrogenchloride; potassium hydroxide; In methanol; water; for 1h; Heating;

DOI:10.1135/cccc19841699

Reference yield: 47.0%

{5-[5-(3-Chloro-phenyl)-furan-2-yl]-tetrazol-2-yl}-acetic acid ethyl ester (93674-59-0) → Potassium; {5-[5-(3-chloro-phenyl)-furan-2-yl]-tetrazol-2-yl}-acetate (93770-42-4)

Guidance literature:

With potassium hydroxide; In methanol; Heating;

DOI:10.1135/cccc19841699

upstream raw materials:

ethyl bromoacetate

5-[5-(3-chloro-phenyl)-furan-2-yl]-1⁽²⁾H-tetrazole

Downstream raw materials:

Potassium; {5-[5-(3-chloro-phenyl)-furan-2-yl]-tetrazol-2-yl}-acetate

{5-[5-(3-Chloro-phenyl)-furan-2-yl]-tetrazol-2-yl}-acetic acid