(R,R)-N,N'-bis(2-chloro-1-(diphenylmethyl)ethyl)-2,2-dimethylmalonamide

Base Information

Chemical Name:(R,R)-N,N'-bis(2-chloro-1-(diphenylmethyl)ethyl)-2,2-dimethylmalonamide
CAS No.:270078-93-8
Molecular Formula:C₃₅H₃₆Cl₂N₂O₂
Molecular Weight:587.589
Hs Code.:

Synonyms:(R,R)-N,N'-bis(2-chloro-1-(diphenylmethyl)ethyl)-2,2-dimethylmalonamide

Suppliers and Price of (R,R)-N,N'-bis(2-chloro-1-(diphenylmethyl)ethyl)-2,2-dimethylmalonamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R,R)-N,N'-bis(2-chloro-1-(diphenylmethyl)ethyl)-2,2-dimethylmalonamide

Chemical Property:

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Technology Process of (R,R)-N,N'-bis(2-chloro-1-(diphenylmethyl)ethyl)-2,2-dimethylmalonamide

There total 2 articles about (R,R)-N,N'-bis(2-chloro-1-(diphenylmethyl)ethyl)-2,2-dimethylmalonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: N,N'-bis-(1-hydroxymethyl-2,2-diphenyl-ethyl)-2,2-dimethyl-malonamide

: 270078-93-8
(R,R)-N,N'-bis(2-chloro-1-(diphenylmethyl)ethyl)-2,2-dimethylmalonamide

Guidance literature:: With thionyl chloride; In chloroform; for 5h; Heating;
DOI:10.1246/bcsj.73.681

Reference yield:

: 171037-01-7
(R)-2-amino-3,3-diphenyl-1-propanol

: 270078-93-8
(R,R)-N,N'-bis(2-chloro-1-(diphenylmethyl)ethyl)-2,2-dimethylmalonamide

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / CHCl₃ / 2 h / 20 °C

2: 0.68 g / thionyl chloride / CHCl₃ / 5 h / Heating

With thionyl chloride; triethylamine; In chloroform; 1: Acylation / 2: Substitution;
DOI:10.1246/bcsj.73.681