4-amino-2-phenyl-8-β-D-erythro-pentofuranosyl-7(8H)-pteridone

Base Information

• Chemical Name: 4-amino-2-phenyl-8-β-D-erythro-pentofuranosyl-7(8H)-pteridone
• CAS No.: 79378-85-1
• Molecular Formula: C₁₇H₁₇N₅O₅
• Molecular Weight: 371.352
• Mol file: 79378-85-1.mol

Synonyms:4-amino-2-phenyl-8-β-D-erythro-pentofuranosyl-7(8H)-pteridone

Chemical Property of 4-amino-2-phenyl-8-β-D-erythro-pentofuranosyl-7(8H)-pteridone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-amino-2-phenyl-8-β-D-erythro-pentofuranosyl-7(8H)-pteridone

There total 5 articles about 4-amino-2-phenyl-8-β-D-erythro-pentofuranosyl-7(8H)-pteridone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

4-amino-8-(2,3,5-tri-O-benzoyl-β-D-erythro-pentofuranosyl)-7(8H)-pteridone (35867-79-9) → 4-amino-2-phenyl-8-β-D-erythro-pentofuranosyl-7(8H)-pteridone (79378-85-1)

Guidance literature:

With sodium methylate; In methanol; for 12h;

DOI:10.1080/15257770903054241

Reference yield: 88.0%

4-amino-2-phenyl-8-(2,3,5-tri-O-benzoyl-β-D-erythro-pentofuranosyl)-7(8H)-pteridone (79378-82-8) → 4-amino-2-phenyl-8-β-D-erythro-pentofuranosyl-7(8H)-pteridone (79378-85-1)

Guidance literature:

With sodium; In methanol; for 12h; Ambient temperature;

Reference yield:

1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose (6974-32-9) → 4-amino-2-phenyl-8-β-D-erythro-pentofuranosyl-7(8H)-pteridone (79378-85-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 75 percent / borotrifluorid etherate / CH₂Cl₂ / 3 h

2: 88 percent / Na / methanol / 12 h / Ambient temperature

With boron trifluoride diethyl etherate; sodium; In methanol; dichloromethane;

upstream raw materials:

4-amino-2-phenyl-8-(2,3,5-tri-O-benzoyl-β-D-erythro-pentofuranosyl)-7(8H)-pteridone

1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose

(2-Phenyl-7-trimethylsilanyloxy-pteridin-4-yl)-trimethylsilanyl-amine

4-amino-2-phenyl-7(8H)-pteridinone