4-amino-8-(2,3,5-tri-O-benzoyl-β-D-erythro-pentofuranosyl)-7(8H)-pteridone

Base Information

Chemical Name:4-amino-8-(2,3,5-tri-O-benzoyl-β-D-erythro-pentofuranosyl)-7(8H)-pteridone
CAS No.:35867-79-9
Molecular Formula:C₃₂H₂₅N₅O₈
Molecular Weight:607.579
Hs Code.:

Synonyms:4-amino-8-(2,3,5-tri-O-benzoyl-β-D-erythro-pentofuranosyl)-7(8H)-pteridone

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-amino-8-(2,3,5-tri-O-benzoyl-β-D-erythro-pentofuranosyl)-7(8H)-pteridone

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Technology Process of 4-amino-8-(2,3,5-tri-O-benzoyl-β-D-erythro-pentofuranosyl)-7(8H)-pteridone

There total 5 articles about 4-amino-8-(2,3,5-tri-O-benzoyl-β-D-erythro-pentofuranosyl)-7(8H)-pteridone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: 6974-32-9
1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose

: 1070990-50-9
4-(Trimethylsilylamino)-7-(trimethylsilyloxy)pteridin

: 35867-79-9
4-amino-8-(2,3,5-tri-O-benzoyl-β-D-erythro-pentofuranosyl)-7(8H)-pteridone

Guidance literature:: With boron trifluoride diethyl etherate; In ethanol; chloroform; for 3h; Ambient temperature;

Reference yield: 22.0%

: 16205-59-7
2,3,5-tri-O-benzoyl-1-bromo-α-D-erythro-pentofuranose

: 22005-66-9
4-amino-7(8H)-pteridone

: 35867-79-9
4-amino-8-(2,3,5-tri-O-benzoyl-β-D-erythro-pentofuranosyl)-7(8H)-pteridone

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; In acetonitrile;
DOI:10.1016/0040-4039(96)01929-6

Reference yield:

: 22005-66-9
4-amino-7(8H)-pteridone

: 35867-79-9
4-amino-8-(2,3,5-tri-O-benzoyl-β-D-erythro-pentofuranosyl)-7(8H)-pteridone

Guidance literature:: Multi-step reaction with 2 steps

1: ammonum sulfate / 3 h / Heating

2: 53 percent / borotrifluorid etherate / ethanol; CHCl₃ / 3 h / Ambient temperature

With ammonium sulfate; boron trifluoride diethyl etherate; In ethanol; chloroform;