3-(4-chlorophenyl)-4-methyl-1H-pyridazin-6-one

Base Information

Chemical Name:3-(4-chlorophenyl)-4-methyl-1H-pyridazin-6-one
CAS No.:52240-09-2
Molecular Formula:C₁₁H₉ClN₂O
Molecular Weight:220.658
Hs Code.:
DSSTox Substance ID:DTXSID801250159
Nikkaji Number:J284.473G

Synonyms:52240-09-2;SCHEMBL8481283;DTXSID801250159;AKOS012080365;6-(4-Chlorophenyl)-5-methyl-3(2H)-pyridazinone

Suppliers and Price of 3-(4-chlorophenyl)-4-methyl-1H-pyridazin-6-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-(4-chlorophenyl)-4-methyl-1H-pyridazin-6-one

Chemical Property:

XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:220.0403406
Heavy Atom Count:15
Complexity:328

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC(=O)NN=C1C2=CC=C(C=C2)Cl

Technology Process of 3-(4-chlorophenyl)-4-methyl-1H-pyridazin-6-one

There total 4 articles about 3-(4-chlorophenyl)-4-methyl-1H-pyridazin-6-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: C₁₈H₁₅ClN₂O

: 52240-09-2
6-(4-chloro-phenyl)-5-methyl-2H-pyridazin-3-one

Guidance literature:: With aluminium trichloride; In toluene; at 140 ℃; for 0.0833333h; microwave irradiation;
DOI:10.1016/j.tetlet.2007.09.013

Reference yield: 7.0%

: 117808-91-0
3-(4-chlorobenzoyl)-3-butenoic acid

: 64-19-7,77671-22-8
acetic acid

: 127847-33-0
[1-Acetyl-3-(4-chloro-phenyl)-4,5-dihydro-1H-pyrazol-4-yl]-acetic acid

: 52240-09-2
6-(4-chloro-phenyl)-5-methyl-2H-pyridazin-3-one

Guidance literature:: With hydrazine hydrate; for 3h; Heating;
DOI:10.1002/jhet.5570270217

Reference yield:

: 21034-24-2
β-(4-chlorobenzoyl)-γ-butyrolactone

: 52240-09-2
6-(4-chloro-phenyl)-5-methyl-2H-pyridazin-3-one

Guidance literature:: Multi-step reaction with 2 steps

1: 91 percent / sodium methoxide / methanol / 0.25 h / Ambient temperature

2: 8 percent / hydrazine hydrate / acetic acid / 3 h / Heating

With sodium methylate; hydrazine hydrate; In methanol; acetic acid;
DOI:10.1002/jhet.5570270217