Z-4-methylstyrylthioacetic acid

Base Information

• Chemical Name: Z-4-methylstyrylthioacetic acid
• CAS No.: 155782-81-3
• Molecular Formula: C₁₁H₁₂O₂S
• Molecular Weight: 208.281
• Mol file: 155782-81-3.mol

Synonyms:Z-4-methylstyrylthioacetic acid

Chemical Property of Z-4-methylstyrylthioacetic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Z-4-methylstyrylthioacetic acid

There total 1 articles about Z-4-methylstyrylthioacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

mercaptoacetic acid (68-11-1) + 4-n-methylphenylacetylene (766-97-2) → Z-4-methylstyrylthioacetic acid (155782-81-3)

Guidance literature:

With sodium hydroxide; In methanol; for 24h; Heating;

Reference yield: 55.0%

Z-4-methylstyrylthioacetic acid (155782-81-3) → Z-4-methylstyrylsulfonyl acetic acid (155782-80-2)

Guidance literature:

With dihydrogen peroxide; acetic acid; at 20 ℃; for 51h;

Reference yield:

Z-4-methylstyrylthioacetic acid (155782-81-3) → (2S,3R,5S)-1,1-Dioxo-3-phenyl-5-p-tolyl-1λ6-thiomorpholine-2-carboxylic acid methyl ester

Guidance literature:

Multi-step reaction with 3 steps

1: 30percent H₂O₂, gl. AcOH

2: 70 percent / conc. H₂SO₄ / 5 h / Heating

3: NH₄OAc / methanol / Heating

With sulfuric acid; ammonium acetate; dihydrogen peroxide; acetic acid; In methanol;

upstream raw materials:

mercaptoacetic acid

4-n-methylphenylacetylene

Downstream raw materials:

Z-4-methylstyrylsulfonyl acetic acid

methyl Z-4-methylstyrylsulfoyl acetate

ethyl Z-4-methylstyrylsulfonyl acetate

C₁₈H₁₈O₃S