[ (4-FLUORO-BENZVL)-R₄-METHVL-2-(4-TRIFLUOROMETHVL-PHENVL)-THIAZOL-5-VLL-AMINE]

Base Information

Chemical Name:[ (4-FLUORO-BENZVL)-R₄-METHVL-2-(4-TRIFLUOROMETHVL-PHENVL)-THIAZOL-5-VLL-AMINE]
CAS No.:639784-41-1
Molecular Formula:C₁₈H₁₄F₄N₂S
Molecular Weight:366.382
Hs Code.:

[ (4-FLUORO-BENZVL)-R<sub>4</sub>-METHVL-2-(4-TRIFLUOROMETHVL-PHENVL)-THIAZOL-5-VLL-AMINE]

Synonyms:[ (4-FLUORO-BENZVL)-R₄-METHVL-2-(4-TRIFLUOROMETHVL-PHENVL)-THIAZOL-5-VLL-AMINE]

Suppliers and Price of [ (4-FLUORO-BENZVL)-R₄-METHVL-2-(4-TRIFLUOROMETHVL-PHENVL)-THIAZOL-5-VLL-AMINE]

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of [ (4-FLUORO-BENZVL)-R₄-METHVL-2-(4-TRIFLUOROMETHVL-PHENVL)-THIAZOL-5-VLL-AMINE]

Chemical Property:

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Technology Process of [ (4-FLUORO-BENZVL)-R₄-METHVL-2-(4-TRIFLUOROMETHVL-PHENVL)-THIAZOL-5-VLL-AMINE]

There total 6 articles about [ (4-FLUORO-BENZVL)-R₄-METHVL-2-(4-TRIFLUOROMETHVL-PHENVL)-THIAZOL-5-VLL-AMINE] which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 639784-40-0
(4-FLUORO-BENZYLIDENE)-[4-METHYL-2-(4-TRIFLUOROMETHYL-PHENYL)-THIAZOL-5-YL]-amine

: 639784-41-1
[ (4-FLUORO-BENZVL)-R₄-METHVL-2-(4-TRIFLUOROMETHVL-PHENVL)-THIAZOL-5-VLL-AMINE]

Guidance literature:: With sodium tetrahydroborate; for 0.25h;

Reference yield:

: 639784-20-6
[4-METHYL-2-(4-TRIFLUOROMETHYL-PHENYL)-THIAZOL-5-YI]-CARBAMIC acid TERT-BUTYL ester

: 639784-41-1
[ (4-FLUORO-BENZVL)-R₄-METHVL-2-(4-TRIFLUOROMETHVL-PHENVL)-THIAZOL-5-VLL-AMINE]

Guidance literature:: Multi-step reaction with 3 steps

1: trifluoroacetic acid / 1 h

2: 4-fluorobenzaldehyde / ethanol

3: sodium tetrahydroborate / 0.25 h

With sodium tetrahydroborate; 4-fluorobenzaldehyde; trifluoroacetic acid; In ethanol;

Reference yield:

: 144059-86-9
4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxylic acid

: 639784-41-1
[ (4-FLUORO-BENZVL)-R₄-METHVL-2-(4-TRIFLUOROMETHVL-PHENVL)-THIAZOL-5-VLL-AMINE]

Guidance literature:: Multi-step reaction with 4 steps

1: diphenyl phosphoryl azide; triethylamine / tert-butyl alcohol / 2 h

2: trifluoroacetic acid / 1 h

3: 4-fluorobenzaldehyde / ethanol

4: sodium tetrahydroborate / 0.25 h

With sodium tetrahydroborate; diphenyl phosphoryl azide; 4-fluorobenzaldehyde; triethylamine; trifluoroacetic acid; In ethanol; tert-butyl alcohol;