(5-fluoro-2-hydroxyphenyl)-3-furanylmethanone

Base Information

Chemical Name:(5-fluoro-2-hydroxyphenyl)-3-furanylmethanone
CAS No.:177597-53-4
Molecular Formula:C₁₁H₇FO₃
Molecular Weight:206.173
Hs Code.:

Synonyms:(5-fluoro-2-hydroxyphenyl)-3-furanylmethanone

Suppliers and Price of (5-fluoro-2-hydroxyphenyl)-3-furanylmethanone

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (5-fluoro-2-hydroxyphenyl)-3-furanylmethanone

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Technology Process of (5-fluoro-2-hydroxyphenyl)-3-furanylmethanone

There total 3 articles about (5-fluoro-2-hydroxyphenyl)-3-furanylmethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 177597-48-7
3-furancarboxylic acid 4-fluorophenyl ester

: 177597-53-4
(5-fluoro-2-hydroxyphenyl)-3-furanylmethanone

Guidance literature:: With aluminium trichloride; at 150 - 180 ℃; for 0.333333h;
DOI:10.1002/ardp.19963290407

Reference yield:

: 488-93-7
3-Furoic acid

: 177597-53-4
(5-fluoro-2-hydroxyphenyl)-3-furanylmethanone

Guidance literature:: Multi-step reaction with 3 steps

1: SOCl₂ / 18 h / Ambient temperature

2: 99 percent / Et₃N / diethyl ether / 1 h / Heating

3: 69 percent / AlCl₃ / 0.33 h / 150 - 180 °C

With aluminium trichloride; thionyl chloride; triethylamine; In diethyl ether;
DOI:10.1002/ardp.19963290407

Reference yield:

: 26214-65-3
furan-3-carbonyl chloride

: 177597-53-4
(5-fluoro-2-hydroxyphenyl)-3-furanylmethanone

Guidance literature:: Multi-step reaction with 2 steps

1: 99 percent / Et₃N / diethyl ether / 1 h / Heating

2: 69 percent / AlCl₃ / 0.33 h / 150 - 180 °C

With aluminium trichloride; triethylamine; In diethyl ether;
DOI:10.1002/ardp.19963290407