Benzenemethanol, 2-nitro-, phenylcarbamate (ester) (9CI)

Base Information

• Chemical Name: Benzenemethanol, 2-nitro-, phenylcarbamate (ester) (9CI)
• CAS No.: 74109-35-6
• Molecular Formula: C₁₄H₁₂N₂O₄
• Molecular Weight: 272.26
• Mol file: 74109-35-6.mol

Synonyms:Benzenemethanol, 2-nitro-, phenylcarbamate (ester) (9CI)

Chemical Property of Benzenemethanol, 2-nitro-, phenylcarbamate (ester) (9CI)

Chemical Property:

• PSA: 84.15000
• LogP: 3.93970

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzenemethanol, 2-nitro-, phenylcarbamate (ester) (9CI)

There total 2 articles about Benzenemethanol, 2-nitro-, phenylcarbamate (ester) (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Nitrobenzyl alcohol (612-25-9) + phenyl isocyanate (103-71-9) → 2-nitrobenzyl phenylcarbamate (74109-35-6)

Guidance literature:

With pyridine; for 0.0833333h;

DOI:10.1021/jm00182a027

Reference yield:

Formanilid (103-70-8) → 2-nitrobenzyl phenylcarbamate (74109-35-6)

Guidance literature:

Multi-step reaction with 2 steps

1: bis-[(trifluoroacetoxy)iodo]benzene / 1,2-dichloro-ethane / 0.03 h / Molecular sieve; Inert atmosphere

2: 1,2-dichloro-ethane / 1 h / 60 °C / Molecular sieve; Inert atmosphere

With bis-[(trifluoroacetoxy)iodo]benzene; In 1,2-dichloro-ethane;

DOI:10.1039/c4ob00066h

Reference yield:

2-nitrobenzyl phenylcarbamate (74109-35-6) → 2-nitrosobenzaldehyde (29809-25-4) + aniline (62-53-3)

Guidance literature:

Quantum yield; Irradiation;

DOI:10.1016/0040-4039(88)80017-0

upstream raw materials:

2-Nitrobenzyl alcohol

phenyl isocyanate

Formanilid

Downstream raw materials:

2-nitrosobenzaldehyde

aniline

Refernces

• 1、 Teicher,Sartorelli. "Nitrobenzyl halides and carbamates as prototype bioreductive alkylating agents". . p. 955 - 960. Retrieved 2007/10/02.