r-3-phenyl-2-trans-carbethoxy-2-ethenyloxirane

Base Information

• Chemical Name: r-3-phenyl-2-trans-carbethoxy-2-ethenyloxirane
• CAS No.: 124826-99-9
• Molecular Formula: C₁₃H₁₄O₃
• Molecular Weight: 218.252
• Mol file: 124826-99-9.mol

Synonyms:r-3-phenyl-2-trans-carbethoxy-2-ethenyloxirane

Chemical Property of r-3-phenyl-2-trans-carbethoxy-2-ethenyloxirane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of r-3-phenyl-2-trans-carbethoxy-2-ethenyloxirane

There total 1 articles about r-3-phenyl-2-trans-carbethoxy-2-ethenyloxirane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-bromo-cis-crotonic acid ethyl ester (51263-38-8) + benzaldehyde (100-52-7) → r-3-phenyl-2-trans-carbethoxy-2-ethenyloxirane (124826-99-9)

Guidance literature:

With lithium diisopropyl amide; Yield given. Multistep reaction; 1.) THF, HMPA, -110 deg C,2.) THF, -105 deg C, 25 min, 3.) THF, -105 deg C, 0.5 h, then -78 deg C, 1 h;

DOI:10.1016/S0040-4020(01)80129-0

Reference yield: 95.0%

r-3-phenyl-2-trans-carbethoxy-2-ethenyloxirane (124826-99-9) → 5-phenyl-2-carbethoxy-2-oxolene (124827-00-5)

Guidance literature:

at 500 ℃; under 0.02 Torr;

DOI:10.1016/S0040-4020(01)80129-0

upstream raw materials:

2-bromo-cis-crotonic acid ethyl ester

benzaldehyde

Downstream raw materials:

5-phenyl-2-carbethoxy-2-oxolene