N-(4-methoxybenzyl)-N-<(2R)-2-benzyloxymethyl-1-cyanopropyl>-2-bromoacetamide

Base Information

Chemical Name:N-(4-methoxybenzyl)-N-<(2R)-2-benzyloxymethyl-1-cyanopropyl>-2-bromoacetamide
CAS No.:130533-05-0
Molecular Formula:C₂₂H₂₅BrN₂O₃
Molecular Weight:445.356
Hs Code.:

Synonyms:N-(4-methoxybenzyl)-N-<(2R)-2-benzyloxymethyl-1-cyanopropyl>-2-bromoacetamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(4-methoxybenzyl)-N-<(2R)-2-benzyloxymethyl-1-cyanopropyl>-2-bromoacetamide

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Technology Process of N-(4-methoxybenzyl)-N-<(2R)-2-benzyloxymethyl-1-cyanopropyl>-2-bromoacetamide

There total 3 articles about N-(4-methoxybenzyl)-N-<(2R)-2-benzyloxymethyl-1-cyanopropyl>-2-bromoacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 130533-04-9
(3R)-2-(4-methoxybenzylamino)-3-benzyloxymethylbutyronitrile

: 598-21-0
2-Bromoacetyl bromide

: 130533-05-0
N-(4-methoxybenzyl)-N-<(2R)-2-benzyloxymethyl-1-cyanopropyl>-2-bromoacetamide

Guidance literature:: With triethylamine; In tetrahydrofuran; at 0 ℃; for 1h;

Reference yield:

: 79027-28-4
(2S)-3-(benzyloxy)-2-methylpropanal

: 130533-05-0
N-(4-methoxybenzyl)-N-<(2R)-2-benzyloxymethyl-1-cyanopropyl>-2-bromoacetamide

Guidance literature:: Multi-step reaction with 2 steps

1: 100 percent / 20percent aq. HCl / H₂O; methanol / 2 h / Ambient temperature

2: 100 percent / triethylamine / tetrahydrofuran / 1 h / 0 °C

With hydrogenchloride; triethylamine; In tetrahydrofuran; methanol; water;

Reference yield:

: 2393-23-9
4-methoxy-benzylamine

: 130533-05-0
N-(4-methoxybenzyl)-N-<(2R)-2-benzyloxymethyl-1-cyanopropyl>-2-bromoacetamide

Guidance literature:: Multi-step reaction with 2 steps

1: 100 percent / 20percent aq. HCl / H₂O; methanol / 2 h / Ambient temperature

2: 100 percent / triethylamine / tetrahydrofuran / 1 h / 0 °C

With hydrogenchloride; triethylamine; In tetrahydrofuran; methanol; water;