C₇H₁₃ClHgO₅

Base Information

• Chemical Name: C₇H₁₃ClHgO₅
• CAS No.: 102628-74-0
• Molecular Formula: C₇H₁₃ClHgO₅
• Molecular Weight: 413.22
• Mol file: 102628-74-0.mol

Synonyms:C₇H₁₃ClHgO₅

Chemical Property of C₇H₁₃ClHgO₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₇H₁₃ClHgO₅

There total 2 articles about C₇H₁₃ClHgO₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ D-Glucal-chlorquecksilber-methoxid (3470-34-6,6641-38-9,102628-74-0)

Guidance literature:

D-Glucal-3.4.6-triacetat-chlorquecksilber-methoxid, NaOCH3/Methanol (Raumtemp., ueber Nacht);

DOI:10.1021/ja00870a036

Reference yield:

→ D-Glucal-chlorquecksilber-methoxid (3470-34-6,6641-38-9,102628-74-0)

Guidance literature:

D-Glucal-acetoxyquecksilber-methoxid/Methanol, wss. KCl-Lsg. (2h, Raumtemp.) nebenanderen Produkten;

DOI:10.1021/ja00870a036

Reference yield:

C7H13ClHgO5 (102628-74-0) → mevastatin (73573-88-3,58948-09-7)

Guidance literature:

Multi-step reaction with 13 steps

1: sodium borohydride / methanol / 0.5 h / 0 °C

2: pyridine / 18 h

3: 1.) sodium hydride, 2.) 1-<(2,4,6-triisopropylphenyl)sulfonyl>imidazole / 1.) HMPA, from 0 deg C to 25 deg C, 2 h, 2.) HMPA, THF, from -23 deg C to 0 deg C, 3 h

4: 95 percent / LiAlH₄ / diethyl ether / -15 °C

5: 90 percent / Li, NH₃ (liquid) / tetrahydrofuran

6: 87 percent / pyridine / 1 h / 25 °C

7: toluene / 7 h / Irradiation

8: imidazole / dimethylformamide / 23 °C

9: 1.) O₃, 2.) dimethyl sulfide / 1.) methanol

10: CH₂Cl₂ / 18 h

12: 10percent aq. HCl / tetrahydrofuran / 0.33 h / 45 - 55 °C

13: Ag₂CO₃/Celite / toluene / 2 h / 95 °C

With pyridine; 1H-imidazole; hydrogenchloride; sodium tetrahydroborate; lithium aluminium tetrahydride; dimethylsulfide; Celite; ammonia; lithium; sodium hydride; ozone; silver carbonate; 1-[(2,4,6-triisopropylphenyl)sulfonyl]-1H-imidazole; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; N,N-dimethyl-formamide; toluene;

DOI:10.1021/jo00363a016

Downstream raw materials:

methyl 2-deoxy-6-O-(triphenylmethyl)-α-D-arabinohexopyranoside

mevastatin

methyl 2,4-dideoxy-6-O-(triphenylmethyl)-α-D-erythro-hexopyranoside

methyl 3,4-anhydro-2-deoxy-6-O-(triphenylmethyl)-α-D-ribo-hexopyranoside