α-cyclopentyl-1,5,6,8-tetramethoxy-4-(methoxy-d₃)-3-(phenylethynyl)-2-naphthalenemethanol

Base Information

• Chemical Name: α-cyclopentyl-1,5,6,8-tetramethoxy-4-(methoxy-d₃)-3-(phenylethynyl)-2-naphthalenemethanol
• CAS No.: 139219-33-3
• Molecular Formula: C₂₉H₃₂O₆
• Molecular Weight: 479.546

Synonyms:α-cyclopentyl-1,5,6,8-tetramethoxy-4-(methoxy-d₃)-3-(phenylethynyl)-2-naphthalenemethanol

Chemical Property of α-cyclopentyl-1,5,6,8-tetramethoxy-4-(methoxy-d₃)-3-(phenylethynyl)-2-naphthalenemethanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of α-cyclopentyl-1,5,6,8-tetramethoxy-4-(methoxy-d₃)-3-(phenylethynyl)-2-naphthalenemethanol

There total 4 articles about α-cyclopentyl-1,5,6,8-tetramethoxy-4-(methoxy-d₃)-3-(phenylethynyl)-2-naphthalenemethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

<<3-bromo-4,5,7,8-tetramethoxy-2-(phenylethynyl)-1-naphthalenyl>oxy>triethylsilane (139219-30-0) → α-cyclopentyl-1,5,6,8-tetramethoxy-4-(methoxy-d3)-3-(phenylethynyl)-2-naphthalenemethanol (139219-33-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 96 percent / Bu₄NF, AcOH / tetrahydrofuran / 0.5 h

2: 81 percent / NaH (60percent in oil) / dimethylformamide / 2.5 h / Ambient temperature

3: 1) n-BuLi / 1) THF, hexane, -78 deg C, 5 min, 2) THF, hexane, -78 deg C, 20 min

With n-butyllithium; tetrabutyl ammonium fluoride; sodium hydride; acetic acid; In tetrahydrofuran; N,N-dimethyl-formamide;

DOI:10.1016/S0040-4020(01)88016-9

Reference yield:

3-bromo-4,5,7,8-tetramethoxy-2-(phenylethynyl)-1-naphthalenol (139219-31-1) → α-cyclopentyl-1,5,6,8-tetramethoxy-4-(methoxy-d3)-3-(phenylethynyl)-2-naphthalenemethanol (139219-33-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 81 percent / NaH (60percent in oil) / dimethylformamide / 2.5 h / Ambient temperature

2: 1) n-BuLi / 1) THF, hexane, -78 deg C, 5 min, 2) THF, hexane, -78 deg C, 20 min

With n-butyllithium; sodium hydride; In N,N-dimethyl-formamide;

DOI:10.1016/S0040-4020(01)88016-9

Reference yield:

2-bromo-5,6,8-trimethoxy-3-(phenylethynyl)-4-<(triethylsilyl)oxy>-1-naphthalenol → α-cyclopentyl-1,5,6,8-tetramethoxy-4-(methoxy-d3)-3-(phenylethynyl)-2-naphthalenemethanol (139219-33-3)

Guidance literature:

Multi-step reaction with 4 steps

1: 1) Na₂S₂O₄, Bu₄NBr, 2) 2N NaOH / 1) H₂O, CH₂Cl₂, 30 min, RT, 2) H₂O, CH₂Cl₂, overnight

2: 96 percent / Bu₄NF, AcOH / tetrahydrofuran / 0.5 h

3: 81 percent / NaH (60percent in oil) / dimethylformamide / 2.5 h / Ambient temperature

4: 1) n-BuLi / 1) THF, hexane, -78 deg C, 5 min, 2) THF, hexane, -78 deg C, 20 min

With sodium hydroxide; n-butyllithium; sodium dithionite; tetrabutyl ammonium fluoride; tetrabutylammomium bromide; sodium hydride; acetic acid; In tetrahydrofuran; N,N-dimethyl-formamide;

DOI:10.1016/S0040-4020(01)88016-9

upstream raw materials:

cyclopentanealdehyde

2-bromo-1,5,6,8-tetramethoxy-4-(methoxy-d₃)-3-(phenylethynyl)naphthalene

3-bromo-4,5,7,8-tetramethoxy-2-(phenylethynyl)-1-naphthalenol

<<3-bromo-4,5,7,8-tetramethoxy-2-(phenylethynyl)-1-naphthalenyl>oxy>triethylsilane

Downstream raw materials:

<1-(phenylseleno)-cyclopentyl><1,5,6,8-tetramethoxy-4-(methoxy-d₃)-3-(phenylethynyl)-2-naphthalenyl>methanone

α-cyclopentyl-1,5,6,8-tetramethoxy-4-(methoxy-d₃)-3-(phenylethynyl)-2-naphthalenemethanone

5,6,8,9-tetramethoxy-4-(methoxy-d₃)-3-(phenylmethylene)spiro<2H-benzindene-2,1'-cyclopentan>-1(3H)-one

3)-3-(phenylethynyl)-2-naphthalenyl>methoxy>trimethylsilane

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 139219-33-3 α-cyclopentyl-1,5,6,8-tetramethoxy-4-(methoxy-d₃)-3-(phenylethynyl)-2-naphthalenemethanol

Send

Send

Metric Ton KG G Pound L ML

Send

Send